- Joined
- Mar 15, 2009
- Messages
- 1,551
I am. just 20 mg and stay on it for now.
What dose for someone that has no bo problems and nust wants the protective effects ?IMO one of the benefits that many overlook as a benefit of Telmisartan is its ability to regulate inflammation and lower CRP.
The two things every bodybuilder should do- keep BP and inflammation in check this med does. Need I say more.
C-reactive protein (CRP)-lowering agents - PubMed
C-reactive protein (CRP) plays a role in the pathogenesis of cardiovascular disease. It is a marker and predictor of cardiovascular disease. CRP possesses numerous cardiovascular effects (clotting, generation of oxygen radicals, increase in the expression of adhesion molecules and plasminogen...pubmed.ncbi.nlm.nih.gov
Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation - PubMed
Our present study indicates a unique beneficial aspect of telmisartan: it may work as an anti-inflammatory agent against AGE by suppressing RAGE expression via PPAR-gamma activation in the liver and may play a protective role in vascular injury in diabetes.pubmed.ncbi.nlm.nih.gov
Impact of telmisartan on the inflammatory state in patients with coronary atherosclerosis--influence on IP-10, TNF-α and MCP-1 - PubMed
Telmisartan reduced blood pressure in patients with atherosclerosis and arterial hypertension within a short time period, whereas the inflammatory status of these patients remained largely unchanged. An involvement of telmisartan in the regulation of inflammatory and anti-inflammatory mediators...pubmed.ncbi.nlm.nih.gov
Unless you have elevated BP or high CRP you don’t need it IMO.What dose for someone that has no bo problems and nust wants the protective effects ?
Edema is pretty common w amlodipine. Taking the amlodipine with an ACE-I or ARB can help to reduce the edema. Something abt each drugs effect on either side of our capillary bed helps to positively alter the pressure changes that result in the edema. Maybe ask your doc to add a low dose of an ACE-I or ARB and run it with 5mg amlodipine. Generally good to avoid polypharmacy but 2+ pitting edema is pretty badWas.
80mg/day just wasn't getting me down low enough.
Went back to Amlodipine (Norvasc) 10mg/day.
Keeps me in the 125-130/70 range.
Only frustration I have is the 2+ pitting edema in my shins it can cause.