In my opinion:
1. A drug that reduces hunger is likely not going to really work with the obese population because hunger is very rarely the reason behind their overreating.
2. Supply chain problems are increasing food prices. But it seems to affect perishable foods more (meat and other animal products, vegetables, fruits, etc.) and highly-processed crap is less expensive to start with. So, if anything, price increases due to supply chain issues, people might start consuming more crap and less "quality" foods.
3. I'm not saying that the crazy conditions we had in the past 2 years will keep up, or if things get better or worse (could be some massive societal changes), but I believe that there is a strong connection between the overall mood of the population and over-indulging on "pleasure foods". Basically you feel like crap, almost depressed, and you eat crap to get a quick "pleasure hit". It's no surprise that during the "pandemic" there was an average weight gain of 20lbs or more in the population (a decrease in activity level also played a role).
4. If we keep moving toward the "acceptance/equaiity above everything else" then there will be less and less incentive to avoid getting fat. Heck, it is even frowned upon to talk about the health risks of obesity now! That's seen as fat-phobia. Like it or not, the main driver of significant personal changes are 1) social acceptance and 2) survival. So if being obese loses all negative stigma and we avoid mentioning the health risks, then the motivation to avoid becoming obese, or lose fat if we have too much, will get lower and lower. The cancel diet culture (i.e. eating properly and exercising) is gaining traction to the point of being in great shape is seen by many as something negative.