Its absolutely a thing. You can call it whatever you want - 'de or re - sensitizing', down regulation, whatever, it doesnt really matter.
One non reviewed peer paper comes out saying it isnt a thing and every forum bro regurgitates the same thing...try it for yourself and see if it works.
Best thing i can compare it to is having your body in a primed state. Ready to uptake food, training, etc. Body isnt inflamed, insulin sensitive, joints feel great.
Or keep blasting 500 test year round add clen and tren i the spring so you look decent/better than guys not running gear.
@Big Dave Smith - I wasnt referring to you, but you're still small. All that BJJ made you soft /s