I thought calcification was a response to black build up. By what mechanism do statins make this worse?increase calcium build up in the arteries
I thought calcification was a response to black build up. By what mechanism do statins make this worse?increase calcium build up in the arteries
“Studies show that, in humans, increased coronary calcification has been observed starting after about 6 years of statin treatment. In our study, the aortic calcium mineral content assessed by µCT imaging showed a significant progression of calcification with aging in both the control and pravastatin-treated groups.Jan 21, 2021”x + y = "we don't have a clue"
Exactly! Patients prescribed the highest doses of statins, despite achieving low levels of cholesterol, had changes in plaque calcification that were nearly double the changes in patients who received no statins, and greater than changes in those who received low-intensity statin therapy, both of which were associated with plaque progression,” says the study’s principal investigator, Rishi Puri, MBBS, PhD.”I thought calcification was a response to black build up. By what mechanism do statins make this worse?
Patients prescribed the highest doses of statins, despite achieving low levels of cholesterol, had changes in plaque calcification that were nearly double the changes in patients who received no statins, and greater than changes in those who received low-intensity statin therapy, both of which were associated with plaque progression,” says the study’s principal investigator, Rishi Puri, MBBS, PhD.”Exactly!
Patients prescribed the highest doses of statins, despite achieving low levels of cholesterol, had changes in plaque calcification that were nearly double the changes in patients who received no statins, and greater than changes in those who received low-intensity statin therapy, both of which were associated with plaque progression,” says the study’s principal investigator, Rishi Puri, MBBS, PhD.”I thought calcification was a response to black build up. By what mechanism do statins make this worse?
This is important observation tells me that statins actually cause hardening of the arteries (Atherosclerosis) while simultaneouslyI thought calcification was a response to black build up. By what mechanism do statins make this worse?
This is important observation tells me that statins might cause hardening of the arteries through calcification.I thought calcification was a response to black build up. By what mechanism do statins make this worse?
And raises the risk for diabetes. Due to some calcification in my arteries 2 cardiologists recommended i go on statins as that is the normal protocol for them. They want me to take a stain to lower my natural LDL level of 75 to get it down to 70. which the second cardiologist said would not matter for me but he was still required to recommend them. People need to look out for themselves and consider Dr.'s advice as well as other sources.Did you know that statins increase calcium build up in the arteries? That can’t be good!
I agree! Especially since statins increases the risk of becoming a diabetic which is the number one cause of artery disease.And raises the risk for diabetes. Due to some calcification in my arteries 2 cardiologists recommended i go on statins as that is the normal protocol for them. They want me to take a stain to lower my natural LDL level of 75 to get it down to 70. which the second cardiologist said would not matter for me but he was still required to recommend them. People need to look out for themselves and consider Dr.'s advice as well as other sources.
Required by whom?And raises the risk for diabetes. Due to some calcification in my arteries 2 cardiologists recommended i go on statins as that is the normal protocol for them. They want me to take a stain to lower my natural LDL level of 75 to get it down to 70. which the second cardiologist said would not matter for me but he was still required to recommend them. People need to look out for themselves and consider Dr.'s advice as well as other sources.
That doesnt really proves that statine is the driver for this process. They are stating that age is the main contributor (in this study).“Studies show that, in humans, increased coronary calcification has been observed starting after about 6 years of statin treatment. In our study, the aortic calcium mineral content assessed by µCT imaging showed a significant progression of calcification with aging in both the control and pravastatin-treated groups.Jan 21, 2021”
Yes, I was caught by the "starting after about 6 years of treatment" portion. I pretty much scrolled past at that point.That doesnt really proves that statine is the driver for this process. They are stating that age is the main contributor (in this study).
I’m not going to try and tell you what to do. But if it were me, I’d get off the statins and optimize my diet and training as you are already considering.I had a quadruple bypass and new mitral valve on September 27...I am currently taking 80 mgs of lipitor (atorvastatin) as well as 6 other meds...my doctor just took me off pacerone...I am feeling pretty good but I can only do about 5 sets in the gym before I am exhausted and light headed...I am considering getting off all the meds and let nature take it's course...
If they tell you to take a blood thinner for that mitral valve don't ditch that thoughI had a quadruple bypass and new mitral valve on September 27...I am currently taking 80 mgs of lipitor (atorvastatin) as well as 6 other meds...my doctor just took me off pacerone...I am feeling pretty good but I can only do about 5 sets in the gym before I am exhausted and light headed...I am considering getting off all the meds and let nature take it's course...
That doesnt really proves that statine is the driver for this process. They are stating that age is the main contributor (in this study).What the study was trying to say is that increasing duration of statin therapy is associated with high coronary artery calcium scores.
I agree!If they tell you to take a blood thinner for that mitral valve don't ditch that though