Yes, apoB is supposedly the more accurate marker of cardiovascular risk, as apoB can identify elevated numbers of small cholesterol. But there’s also arguments against this theory as well. That said, at least four studies have shown a lack of an association between LDL-C and degree of atherosclerosis and coronary calcification. Some doctors believe if high LDL was the major cause of atherosclerosis and heart disease, people with the highest LDL should have shorter lives than people with low values. However, in a recent systematic review of 19 cohort studies including more than 68,000 elderly people (>60 years of age), they found the opposite to be true. There’s still a lot we don’t know about the human body.