With these peps are they still promoting hyperplasia due to elevated igf?
And how Long are they raised vs hgh.
My buddies levels from generic black top gh is 365 from 5iu.
For 145$ per month that's pretty good. For 290$ he could do 10iu.
Here we have 5 weeks worth giving 415 serum level for 160$
I already purchased cjc so I'm excited.
But I'm still wondering the trade off.
Contribution of satellite cells to IGF-I induced hypertrophy of skeletal muscle.
Barton-Davis ER, Shoturma DI, Sweeney HL.
Department of Physiology, A700 Richards Bldg., University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6085, USA.
Abstract
Insulin-like growth factor I (IGF-I) is critical in promoting growth of skeletal muscle. When IGF-I is introduced into mouse hindlimb muscles by viral-mediated gene transfer, local overexpression of IGF-I produces significant increases in muscle mass and strength compared with untreated controls (Barton-Davis et al. 1998). We have proposed that this functional hypertrophy is primarily owing to the activation of satellite cells which leads to increased muscle regeneration. In order to test if satellite cells are essential in mediating the hypertrophic effects of IGF-I, we used gamma radiation to destroy the proliferative capacity of satellite cells. The right hindlimbs of adult C57BL/6 male mice were subjected to one of the following treatments: (1) 2,500 rad gamma radiation only, (2) viral-mediated gene transfer of IGF-I only, (3) 2,500 rad gamma radiation plus viral-mediated gene transfer of IGF-I, or (4) no intervention as a control. Approximately 4 months after treatment, the extensor digitorum longus muscles (EDL) from both hindlimbs were removed for mechanical and morphological measurements. Treatment with gamma radiation significantly prevented normal growth of the muscle. When combined with IGF-I treatment, approximately half of the IGF-I effect was prevented by gamma radiation treatment. This suggests that the remaining half of IGF-I induced hypertrophy is owing to paracrine/autocrine effects on the adult myofibres. Thus, these data are consistent with a mechanism by which IGF-I induced muscle hypertrophy via a combination of satellite cell activation and increasing protein synthesis in differentiated myofibres.
I have seen where igf levels were still above baseline 28 days after stopping DAC..
And 5 ius = 365 so 8mg dac is close to 7ius.. not too shabbY!!
And I dont think there is a tradeoff.. this is your own bodys GH and IGF not exo gh.. so one can only assume its better for you
can this really be better than taking hgh and getting the serum levels up. 3.5 is not bad considering its usualy .1
Yeah 3.5 isnt bad for the trough level.. take that into consideration along with the pulses and that equals one high igf level..