B-BOY is right!
If the 3 dimensional structure of the 191aa HGH is not folded perfectly it can lead to destruction of the bodies ability to use HGH permanently, even HGH produced in the body.
Even though the generic appears to be working, it can lead to permanent damage of the bodies' ability to use synthetic of pituitary made HGH.
Generic HGH is not the same as pharma grade HGH.
~ Cautions and Potential Problems with So-Called Generic and Compounded Human Growth Hormone (HGH)
"Purification and handling of proteins produced in cell cultures can
too easily produce variations in folding, unfolding, cross-linkages, and variable aggregates of multiple proteins hooked together as dimers and polymers. These can cause immune responses and allergy to HGH, even endogenously produced HGH. Extraction and purification are very complex. Minuscule residues from the cell culture are inevitable and vary from product to product. It is relatively easy to get hormone activity, but extensive human testing is required for to prove safety for any new FOPP, including so-called "generic" HGH."
"To be completely safe, dimers, polymers, aggregates,
improper folding, glycosylation, broken cross-linkages, pyrogens, and contaminants must be strictly controlled during manufacture and packaging. This molecule is fragile and the freeze drying and packaging process can further alter its structure.
Such abnormalities may not block hormone activity, and the product may seem to work quite well in many cases, but the altered molecules may stimulate immune reactions and cause allergy and desensitization to HGH, with subsequent and permanent decrease in hormone response. Such autoimmunity has been reported with as little as one percent of the injected HGH in an altered form, causing the body to neutralize internally produced as well as injected HGH."