This is what worries me, very much, about this whole class of drugs. It's a crapshoot whether it will work for you or not, all the doctor can say is "Let's give this a try." And if he guesses right, then you feel great, although you may have side effects (short and long term) to deal with. But if he guesses wrong, you're screwed.
I'll be honest and say that I get depressed every time I try to decrease my test dose from supraphysiological levels down to actual TRT levels. Miserable, depressed, and OCD. But then they want to prescribe me an anti-depressant, and to be honest the side effects of those scare me much more than the side effects of the test.
So I just stay on the higher dose of test. Which isn't a solution, but at least I know what to expect from it. :-(
What scares me most, is that my oldest daughter (22) just got prescribed Lexapro, because she is depressed from being stuck at home during the whole COVID-19 thing. Maybe it will be the right thing for her. But maybe it will really mess her up. I just try to make her aware of the potential side effects, and be supportive of her to resolve her depression in other ways.
But how well has that worked for me, really?