Scientist, did you run it ED in the muscle you were training or did you only run it on the days that you were training a lagging bodypart? Also how long did you run it?
Hi Swole,
Well I used it as part of a 15 day Blitz cycle where I run a testosterone, anabolic, gh t3 and insulin/dnp combination for IGF 1 des 3 conversation.
I only injected every training day pre and post in the muscle I trained. Post workout I injected it, drank a protein shake and waited around an hour before I shot my slin and took some dnp.
When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue. The appearance of MGF also initiates the upregulation of new protein synthesis. After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an injectable peptide, and it has been anecdotally shown that injecting it will cause a response in the area resulting in localized muscle growth. (
Mechano Growth Factor (MGF) Profile)
So now we had new found muscle cells from the splicing but what about proliferation and maturing the new muscle cells...at that time I couldn't get my hands on any IGF 1 so I made a plan and run slin with dnp...
The insulin molecule is experiencing N-terminal truncation when coming into
contact with circulatory DNP. When the N-terminal is removed from IGF-1 the
resulting growth factor is called Des (1-3) IGF-1. The result is an anabolic far
more powerful than even IGF-1 itself. This is true of IGF-2 and other growth
factors including insulin. The possibility strongly suggests that the truncated
insulin molecule would more readily fit into and activate the muscle cell IGF-1
receptors as well. (*Rapid stimulation of glucose transport by mitochondrial! uncoupling depends in part on cytosolic Ca2+ and cPKC Z A Khayat, T Tsakiridis, A Ueyama, R Somwar, A Kiip AMERICAN JOURNAL OF PHYSIOLOGY, 275(6 Pt 1):C1487~C1497 1998)