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Does anyone else hear have a pituitary adenoma? These are said to be found in 15-25% of the population, mine was discovered by chance during an MRI and seems to be non functioning meaning it doesn't effect my hormones/anything else. That being said I get MRI's to check up on it and make sure it's not changing, it's 4mm.
I wanted to ask if anyone with a pituitary adenoma had seen any progression upon using HGH or peptides like BPC-157.
There are quite a few studies on HGH due to many adenoma patients needing HGH replacement therapy, HGH seems safe. I've linked the studies below:
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
I could not find anything on BPC-157 and pituitary adenomas, I'm wondering if its growth factors are those that would stimulate a pituitary adenoma to progress. Linking some research below.
BPC-157 Research:
BPC-157: Potential upregulation of VEGF: https://pubmed.ncbi.nlm.nih.gov/20388964/
examine.com
"BPC-157 appears to activate a protein known as VEGFR2 and internalizes it within a cell, which then activates a particular pathway (VEGFR2-Akt-eNOS) that is important in blood vessel production and repair."
"The growth factor EGF-1 may also be related to the observed benefits of BCP-157."
We see information about EGF and VEGF here, not quite sure if those would stimulate growth of pituitary adenomas, hoping to get some feedback from the community. I know this may seem like a ridiculous subject but just figured I'd see if anyone has done research on it or has any first hand experience.
I wanted to ask if anyone with a pituitary adenoma had seen any progression upon using HGH or peptides like BPC-157.
There are quite a few studies on HGH due to many adenoma patients needing HGH replacement therapy, HGH seems safe. I've linked the studies below:
The effect of growth hormone on pituitary tumour growth - PubMed
Despite the limitation of study size, patient case selectivity and treatment modalities, present studies of growth hormone replacement do not appear to demonstrate an increase in pituitary tumour recurrence. Conclusive evidence will only be generated by long-term randomized prospective clinical...
pubmed.ncbi.nlm.nih.gov
Replacement therapy with growth hormone and pituitary tumor recurrence: the relevance of the problem - PubMed
Most cases of adult GH deficiency (AGHD) result from hypothalamic-pituitary tumors or their treatment. Some experimental and clinical observations suggest that GH may possess a mitogenic potential, thus raising the question of whether it is a safe treatment in patients with a previous pituitary...
pubmed.ncbi.nlm.nih.gov
Tumor Recurrence or Regrowth in Adults With Nonfunctioning Pituitary Adenomas Using GH Replacement Therapy - PubMed
The findings in this large study were in line with those reported in literature and provide further evidence that GH-RT does not appear to increase tumor progression risk in NFPA patients. Although only long-term randomized controlled trials will be able to draw firm conclusions, our data...
pubmed.ncbi.nlm.nih.gov
Growth Hormone Therapy Does Not Increase the Risk of Craniopharyngioma and Nonfunctioning Pituitary Adenoma Recurrence - PubMed
Replacement therapy with rhGH is prescribed to patients with adult growth hormone deficiency. Our study found no increased risk of pituitary tumor recurrence.
pubmed.ncbi.nlm.nih.gov
I could not find anything on BPC-157 and pituitary adenomas, I'm wondering if its growth factors are those that would stimulate a pituitary adenoma to progress. Linking some research below.
BPC-157 Research:
BPC-157: Potential upregulation of VEGF: https://pubmed.ncbi.nlm.nih.gov/20388964/
Research Breakdown on BPC-157 - Examine
"The growth factor EGF-1 may also be related to the observed benefits of BCP-157."
We see information about EGF and VEGF here, not quite sure if those would stimulate growth of pituitary adenomas, hoping to get some feedback from the community. I know this may seem like a ridiculous subject but just figured I'd see if anyone has done research on it or has any first hand experience.
