Question on HCG for women and dieting

[Nssca]

Is HCG of any benefit for weight lose for women?
Thanks...
DAT? your thoughts?

 

[mexbeast]

this issue has been debated for over 10 yrs but i have never heard any conclusive facts on wethere it works or not. i to would like to hear if anyone knwoes anything on it, but hcg mimicks lh which would cause a woman to release more estro n progesteron along with the othere female hormones so i dont se how it could help with fat lose!

 

[FasTwitch]

IMO Its the 500kcal/day diet that coincides with the ridiculous scientific speculation that is the only support for the "HCG Diet" as it is called...

A relatively new study shows the seemingly contrary effects on adipose tissue via the LH/HCG receptor pathway. This is a somewhat new discovery as the LH/HCG receptor was not known to be present in adipose tissue at the time this fad HCG diet came into existence which resulted in speculation on possible indirect effects of HCG might have on adipose metabolism.

Anyhow:

In vitro effects of chorionic gonadotropin hormone on human adipose development

Esther Dos Santos, Marie-Noëlle Dieudonné, Marie-Christine Leneveu, René Pecquery, Valérie Serazin and Yves Giudicelli

Service de Biochimie et Biologie Moléculaire, UPRES EA 2493, Faculté de Médecine Paris-Ile de France Ouest, Centre hospitalier de Poissy, Université Versailles St Quentin, 78303 Poissy Cedex, France

(Requests for offprints should be addressed to Y Giudicelli; Email: [email protected])

It is well known that pregnancy is associated with fat weight gain. However, the mechanisms whereby fat mass accumulation is controlled during this period are poorly understood. Therefore, we attempted to determine whether human chorionic gonadotropin (HCG), in vitro, influences human adipose tissue development and/or metabolism. For the first time, HCG/LH receptor was characterized in human adipose cells. We also demonstrated that physiological concentrations of HCG, while unaltering both lipolysis and expression of two markers of lipogenesis (FAS and ADD1) in human mature adipocytes, stimulate human preadipocyte growth via the activation of a protein kinase A-independent mitogen-activated protein kinase/c-fos signaling pathway. HCG also moderately increases the preadipocyte differentiation capacityas reflected by enhanced glycerophosphate dehydrogenase activity and expression of key adipogenic transcriptional factors (C/enhancer-binding protein {alpha} and peroxisome proliferator-activated receptor {gamma} 2). Finally, HCG significantly stimulates the secretion of the proadipogenic factor, leptin, from human adipose tissue. Taken altogether, these data suggest that the proadipogenic effect of HCG in human preadipocytes contributes to explain why increased fat storage occurs during the first trimester of pregnancy.

 

[DatBtrue]

Is HCG of any benefit for weight lose for women?
Thanks...
DAT? your thoughts?

What FasTwitch said.

I looked into it a few months ago and I did find studies that specifically examined it for weight loss. The results were that it doesn't work & is "junk science".

FasTwitch hit the nail on the head as to "why" it works.

 

[Nssca]

Thanks guys.

 

[EasyEJL]

basically the placebo effect makes the fat chicks believe they shouldn't feel hungry or feel exhausted on the 500 cal a day diet, so it works out