another antihistamine question

[repmks]

does anyone use antihistamines regularly? has it affected your training in a negative way? what do you take, for what, and what doseage. thanks for the replies.

 

[BadGenCD]

yes it sort of does...if you look up studies on diphendydramine hcl (benadryl), you will see that because it is an anti-cholinergic, it affects and supresses growth hormone release. I wouldnt use it ALL the time.

 

[smootheavy]

yes it sort of does...if you look up studies on diphendydramine hcl (benadryl), you will see that because it is an anti-cholinergic, it affects and supresses growth hormone release. I wouldnt use it ALL the time.

wow I didnt know that...I also know that it can negatively interact with certain serotonin compounds such as ssri's and ssre's

Anticholinergic means that it blocks the neurotransmitter acetylcholine...here I got this from wiki: http://en.wikipedia.org/wiki/Acetylcholine

Acetylcholine has functions both in the peripheral nervous system (PNS) and in the central nervous system (CNS) as a neuromodulator.

In the PNS, acetylcholine activates muscles, and is a major neurotransmitter in the autonomic nervous system.

In the CNS, acetylcholine and the associated neurons form a neurotransmitter system, the cholinergic system, which tends to cause excitatory actions.


In PNS
In the peripheral nervous system, acetylcholine activates muscles, and is a major neurotransmitter in the autonomic nervous system. When acetylcholine binds to acetylcholine receptors on skeletal muscle fibers, it opens ligand gated sodium channels in the cell membrane. Sodium ions then enter the muscle cell, stimulating muscle contraction. Acetylcholine, while inducing contraction of skeletal muscles, instead induces decreased contraction in cardiac muscle fibers. This distinction is attributed to differences in receptor structure between skeletal and cardiac fibers.



In CNS
In the central nervous system, ACh has a variety of effects as a neuromodulator, e.g., for plasticity and excitability. Other effects are arousal and reward. Damage to the cholinergic system in the brain has been suggested to play a role in the memory deficits associated with Alzheimer's Disease.

Plasticity
ACh is involved with synaptic plasticity, specifically in learning and short-term memory.

 

[repmks]

is this specific to benadryl or is this for antihistamines in general.

 

[full_belly]

specoific to benadryl

 

[ballennonstop]

wow that is terrible..i take diph to sleep all the time