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- Apr 5, 2007
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In layman’s terms- it’s cardio selective and modulates nitric oxide (NO) so has little to no impact on the metabolism in comparison to standard beta blockers.Possibly a dumb question; I know certain beta blockers affect metabolic rate, but if I recall correctly Nebivilol doesn’t correct? I’ve been thinking about adding it in, should I watch the scale for any adjustments dietary-wise that may be necessary?
Someone may argue and say that it still could since it’s slowing the HR. But it’s very selective in this case and doesn’t necessarily translate to slowing of the metabolic pathways as shown below in the study.
Additionally, one is usually taking it to get their HR back into a “healthy” range. Walking around with a spiked heart rate leads nowhere good with health outcomes.
Back to @juiceddunk2.0 log. I’m just pumped he’s picked a show and excited to follow his prep.
Here’s the study:
Metabolic effects and safety profile of nebivolol - PubMed
Nebivolol, compared with classical beta-blockers, exerts a high selectivity for beta-adrenergic receptors and also reduces peripheral vascular resistance by modulating nitric oxide (NO) release. This dual mechanism of action leads to effective control of blood pressure at a low degree of...
pubmed.ncbi.nlm.nih.gov