Pre-mixed IGF shelf life?

[Southern Comfort]

Ive got 3mgs in 3 seperate vials of pre-mixed IGF thats probably 3 years old... let me guess, no good anymore?

 

[123cctv]

Ive got 3mgs in 3 seperate vials of pre-mixed IGF thats probably 3 years old... let me guess, no good anymore?

No matter what it's mixed in (AA?), and even if it was properly handled and stored (hopefully in a fridge?), it's potency will have degraded. However potency doesn't just 'disappear' in one day, decreasing from 100% to 0%. That process takes time and varies.

Not that this is a good measurement in determining potency, but uncut IGF does have a sting on admin....

 

[jm425]

It's lost a lot of potency that's for sure if it wasn't stored in the fridge after reconstitution. You can try using it but I wouldn't.

 

[ddude]

This is of course posted else where on the net, I just dug it up for in here. I'm taking zero credit for this post. I'll bet the same data is somewhere in the search on this forum. Anyhow, hope this helps!

Storage of LR3 IGF-1
*Study conducted by Gropep

The stability of a liquid solution of LR3IGF-I was monitored for a period of two years at storage conditions of -20 C, +4 C, +22 C, and +37 C. The final concentration of LR3IGF-I was in acetic acid. At various time points, samples were taken and compared to a lyophilized control (stored at 4 C). Listed below are the stability results for each respective storage condition.


Storage Condition: -20 C (-4 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years

Storage Condition: +4 C (39.2 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years

Storage Condition: +22 C (71.6 F)
Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years

Storage Condition: +37 C (98.6 F)
Biological Potency No Change up to 1 year
Immunological Activity No Change up to 1 year
Mobility of Protein No Change up to 1 year
Elution Profile by reversed phased HPLC No Change up to 1 year

In conclusion, there is no significant difference in the potency of LR3IGF-I associated with the storage of the liquid formulation when stored at this range of temperatures. There is no evidence for loss of biological activity at any of the tested temperatures when stored as a liquid product. As you can see IGF can be quite stable for even a year at room temperature, but if you want to keep it around for a while then stick it into the fridge. So in my opinion the best way to store LR3 that is suspended in BA (benzoic acid) is in the freezer. The BA won’t allow it to freeze. And if you have it suspended in AA (acetic acid), store it in the fridge.

 

[chris250]

Ive got 3mgs in 3 seperate vials of pre-mixed IGF thats probably 3 years old... let me guess, no good anymore?

my questiong would be why would it be 3 years old ? Or how do you know if its 3 years old ? Or why would you let it sit for 3 years, before deciding to use the IGF ? Just curious thats all