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After reading what i post below, what is your opinion on using proviron through out a cycle to prevent estrogen buildup, and or gyno? This is copy and paste from the article about clomid, nolva, and pct in the article section.
When it comes to anti-estrogens, the best bet may be not in occupying the receptor sites,
as does Clomid, but to compete with the testosterone/estrogen balance. At one time,
Proviron was deemed a valid choice as an anti-estrogen agent until some of the
sophomoric steroid students argued that it didn't have any direct anti-estrogenic
properties. True, but it still looks as if it's the best choice if you feel the need to guard
against estrogen build up. It does so because DHT acts as a gyno antagonist. (Yet
another thing that has been oddly overlooked.) Even when DHT is applied topically it's
been shown to reduce gyno in cases where the gyno hadn't been a chronic condition.
Beyond the direct effect of DHT, Proviron has distinct benefits, the first being that as a
derivative of DHT it isn't capable of forming estrogen, yet it has a much higher affinity
for the aromatase enzyme (which converts testosterone to estrogen) than does
testosterone. That means administering it with another aromatizable compound will
prevent estrogen build up due to the fact that DHT binds to the aromatase enzyme so
strongly. There's also been some suggestion that Proviron may downgrade the actual
estrogen receptor, thereby making it twice as effective at reducing circulating estrogen
levels. And because DHT has such a high affinity for SHBG it leaves more free
testosterone to impart its anabolic effects.
It makes sense that the use of Proviron is a more practical and rational method of dealing
with the possibility of excess estrogen than the aforementioned method of attempting to
add a weaker estrogen in the hopes that it will prevent aromatization.
William Llewellyn touches upon this in Anabolics 2000. He says...
"(Proviron) is in contrast to Nolvadex which only blocks estrogen's ability to bind and
activate receptors in certain tissues." (such as breast tissue)
In other words, the World Anabolic Reference was right when it stated;
"Proviron cures the problem of aromatization at the root while Nolvadex simply cures the
symptoms. "
Proviron in moderate doses has been shown to be remarkably safe and free of side effects
in most men. If you must use an anti-estrogen, Proviron is the way go.
When it comes to anti-estrogens, the best bet may be not in occupying the receptor sites,
as does Clomid, but to compete with the testosterone/estrogen balance. At one time,
Proviron was deemed a valid choice as an anti-estrogen agent until some of the
sophomoric steroid students argued that it didn't have any direct anti-estrogenic
properties. True, but it still looks as if it's the best choice if you feel the need to guard
against estrogen build up. It does so because DHT acts as a gyno antagonist. (Yet
another thing that has been oddly overlooked.) Even when DHT is applied topically it's
been shown to reduce gyno in cases where the gyno hadn't been a chronic condition.
Beyond the direct effect of DHT, Proviron has distinct benefits, the first being that as a
derivative of DHT it isn't capable of forming estrogen, yet it has a much higher affinity
for the aromatase enzyme (which converts testosterone to estrogen) than does
testosterone. That means administering it with another aromatizable compound will
prevent estrogen build up due to the fact that DHT binds to the aromatase enzyme so
strongly. There's also been some suggestion that Proviron may downgrade the actual
estrogen receptor, thereby making it twice as effective at reducing circulating estrogen
levels. And because DHT has such a high affinity for SHBG it leaves more free
testosterone to impart its anabolic effects.
It makes sense that the use of Proviron is a more practical and rational method of dealing
with the possibility of excess estrogen than the aforementioned method of attempting to
add a weaker estrogen in the hopes that it will prevent aromatization.
William Llewellyn touches upon this in Anabolics 2000. He says...
"(Proviron) is in contrast to Nolvadex which only blocks estrogen's ability to bind and
activate receptors in certain tissues." (such as breast tissue)
In other words, the World Anabolic Reference was right when it stated;
"Proviron cures the problem of aromatization at the root while Nolvadex simply cures the
symptoms. "
Proviron in moderate doses has been shown to be remarkably safe and free of side effects
in most men. If you must use an anti-estrogen, Proviron is the way go.
