I have used nolvadex for gyno. When I first noticed I had a little lump under my nipple I started taking it at 40mg ED. I noticed it made it a little smaller but I noticed after a couple of days that it wasnt getting noticeably smaller anymore. I read somewhere to up the dose to 100mg ED and it disappeared within 3 days. After it was gone I stopped taking the nolvadex and it stayed gone.