naturally, test/cort/ are highest in the morning,,,which both modulate E production,,,,test aromatizes,,,cort upregulates aromatase
so E is high in the morning, i believe.
BUT i think you are splitting hair here.....as long as you keep taking it continuously eventually you will acheive lower baseline E circulating,,,dont overthink.
oh take it with fat if its aromasin, macro has been saying this.