Since everyone wants high IGF levels from HGH testing. Why not do IGF instead????
IGF-lr3 is much cheaper. Look at the sponsors here. IGF are so much cheaper trusted & unlikely fake.
I know HGH provides other anti-aging benefits but look at this forum. 80% of use wants fat loss & growth.
So why waste money & fear being fake when we can just use LR3 or DES?
Someone correct me if i'm wrong. I'm just trying to find the logic here.
People are wanting high IGF-1 levels while testing their GH because they are unaware that serum testing will be a much more reliable method of determining their GH potency.
People also way overestimate the importance of hepatic IGF-1 when it comes to muscle growth. The IGF-1 that gets raised during the use of GH is called hepatic IGF-1 because it is made in the liver due to GH. It is actually one of the very ways your body decides that enough GH is being made. The brain perceives this level of IGF-1 and then adjusts its production of GH to keep it within a certain range.
GH also increases IGF-1 BP3 and lowers BP1 and 2.
In order for hepatic IGF-1 to bind well to a receptor it needs a binding protein 3 attached to it. The other binding proteins 1 and 2 are known to inhibit binding to the receptor. GH helps increase the right kind of IGF-1 binding proteins and reduce the kind that are not so good.
GH releases fat from the fat cells. IGF-1 does not do this.
IGF-1 does bind to muscle and liver cells and disposes of glucose, and does not do this at fat cells, so there is a nice transformation effect that happens, but not necessarily does this lead to increased insulin sensitivity.
GH is responsible for the release of two unique kinds of IGF, but they only release within the muscle cell. IGF-1 and IGF-1ec *aka MGF are released within the muscle cell itself due to damage done by exercise and this process is greatly enhanced in the presence of GH.
There is no doubt that IGF-1 LR3 does some cool things for body composition. It does a good job of converting that extra carb we consume into glycogen stored in muscle and liver rather than triglyceride stored in fat.
BUT GH will accomplish the same thing, AND it will increase the proper binding proteins, although IGF-1 LR3 doesn't need that anyways, it's unbind-able due to its LR3 manipulation.
Bottom line is that GH is going to give someone quite a bit more bang than IGF-1 LR3. Plus with IGF-1 LR3, you inhibit your own GH after a while so the results stop coming - this is the problem I see with LR3, not some receptor burnout as others put it.
But given the current climate of crap GH out there, I would recommend anyone wanting a body composition effect to either stick with a very reliable source of GH, and sometimes that means paying more, or buying legitimate IGF DES or LR3. I actually prefer the DES.
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