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Tamoxifen question

trainiac

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Does tamoxifen block estrogen only in breast tissue receptors or does it work body-wide?
 

lntense

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Prevents attachment to receptors in the chest.
 

Swifto

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Does tamoxifen block estrogen only in breast tissue receptors or does it work body-wide?

I believe breast tissue.

Prevents attachment to receptors in the chest.

Tamoxifen is an estrogen receptor (ER) antagonist in other tissues, not only breast tissue. It also acts as an ER agonist in certain tissues such as the endometrial cells in women, as well as bones and the cardiovascular system in humans (males included).
 
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Gunsmith

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Tamoxifen is an estrogen receptor (ER) antagonist in other tissues, not only breast tissue. It also acts as an ER agonist in certain tissues such as the endometrial cells in women, as well as bones and the cardiovascular system in humans (males included).

Exactly , all estrogen receptors , thats what makes it effective for women to diet with
 

Elvia1023

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I know a lot of guys don't want to use AI's due to their effects on cholesterol etc. In that event I would recommend approx 10mg tamoxifen daily on cycle (depending upon your aas doses). After about 1 month get blood work done and see where you are at. If it's not enough I would recommend adding 5mg exemestane daily. That to be is lipid friendly anti-estrogen stack that should benefit many on cycle. Obviously everyones sensitivity to aromatization is different so some may need more and others less.
 

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