- Joined
- Mar 22, 2005
- Messages
- 818
What is the role, if any, of IGF LR3 in contest prep?
I'd rather opt for a short recombinant-IGF-1 variant and use as a "diet insulin" for loading carbs the final week.
Rather not mess with the long lasting R3 attaching to sites I'd rather not attach to.
-FF
Useless. Every medical study shows it doesn’t actually effect igf1 levels in humans. Which is why Medicine tossed it out. And no it’s not because it’s cheap. My per mg it’s more expensive then normal igf1. Spend the money on more gh.
“Don’t use something that medicine rejected”
I'd rather opt for a short recombinant-IGF-1 variant and use as a "diet insulin" for loading carbs the final week.
Rather not mess with the long lasting R3 attaching to sites I'd rather not attach to.
-FF
I believe that it's more hype than concrete duplicatable muscle hypertrophy/regeneration/growth results.
IGF-1 is going to turn a dieting Bodybuilder from a fat oxidizer to a glucose oxidizer and promote cell storage and not influence lipolysis, but possibly be lipogenic.
So in the grand scheme of things -- could you use a few 100 mcg's as a "glucose disposal agent" to load some carbs in a depleted/lean body? Sure, and it should be much "safer" than insulin if that is a huge concern of not feeling confident with using insulin to carb load.
However - I think GH and simply using insulin is the magic, not any variant of IGFs
-FF
http://joe.endocrinology-journals.org/content/205/3/201.full
Conclusions
The GH and IGF1 signaling pathways are important regulators of muscle and bone cell survival and function. The commonly observed decline in circulating GH and IGF1 levels that accompanies aging may contribute to reduced muscle strength and trabecular bone mass.
https://www.ncbi.nlm.nih.gov/pubmed/12671196
Estradiol effects on the growth hormone/insulin-like growth factor-1 axis in amenorrheic athletes.
suggesting that estrogen, exercise, and nutritional deficiencies may have independent effects on the GH/IGF-1 axis.