ADEQUAN?

[CYPHON]

Does anyone have info or experience on it's use? I have developed pretty bad joint damage/tendenitis over the years.
Ive used MSM/glucosamine/chondroitin.......I also used sodium hyaluronic with little success.

 

[xcelbeyond]

Not sure, but isn't pentosan and adequan the same? http://www.professionalmuscle.com/forums/showthread.php?threadid=5681

xcel

 

[Tapout1]

I am on it right now, the stuff will put viox out of Business if they would approve it for human use by the fda.

Here is some info

FAST ACCESS TO THE JOINTS: Beneficial levels of Adequan are already at work in all major joints within two hours after intramuscular injection, with even greater uptake (up to 73% higher) in joint tissues that are inflamed or diseased. LONG-TERM EFFECTS: Adequan relieves the pain and disability of joint damage, and the relief has been shown to last up to 6 months or longer. BREAKS THE DESTRUCTIVE CYCLE: Adequan binds to damaged cartilage and boosts cartilage metabolism, facilitating repair processes. At the same time, it blocks the action of destructive enzymes that promote joint inflammation, break down the synovial fluid, and attack the cartilage. RENEWS THE JOINT FLUID: Adequan stimulates the synovial membrane to manufacture new synovial fluid to replace the thin, degraded fluid of joint disease. By doing so, Adequan helps lubricate, nourish, and clean the cartilage.



First, Adequan has important antiinflammatory effects, so it is able to provide relief from the symptoms of joint damage: heat, swelling, pain and lameness. And Adequan can be found in synovial fluid at full therapeutic levels within only two hours of an intramuscular injection. Also, Adequan is a product with potent ability to block the action of the destructive enzymes that threaten to perpetuate the joint inflammation, attack the cartilage and break down synovial fluid.

Second, Adequan also stimulates the synovial membrane to manufacture new, viscous synovial fluid to replace the thin fluid that was produced when the joint became injured. By improving this fluid, Adequan helps the joint regain its ability to lubricate and guard itself against further inflammation, and helps reestablish nutrition to the cartilage.

And, Adequan attaches itself to damaged cartilage where it has a positive effect on cartilage metabolism. This should favor the cartilage repair process.

Adequan is the only joint treatment proven to reduce the inflammation and pain of degenerative joint disease, but also to help stop the degenerative process while stimulating the production of new joint fluid and new cartilage components. You are no longer just treating symptoms: you're doing something to help stop the degenerative process.

DOSAGE AND ADMINISTRATION: The recommended dose of Adequan® in horses is 250 mg (1 vial) once a week for five weeks, intra-articularly. The joint area must be shaved, cleansed and sterilized as in a surgical procedure prior to injection. Do not mix Adequan® with other drugs or solvents.


ACA Journal of Chiropractic/November 1990
Reprinted with permission. Ó 1990, all rights reserved.
Luke R. Bucci, Ph.D.

From the medical schools of Kumamoto, Matsumoto, Nagoya, Aichi, Tohuku, and Inatsuki, 26 orthopedic clinics participated in a double-blind study of 120 patients with osteoarthritis of the knee given intra-articular injections of either 1 mg arteparon (control group), or 50 mg Arteparon.Ò Five total injections were given at weekly intervals for five weeks. Assessment of treatment found that 71 percent of high-dose patients showed improvement, and that 41 percent of controls also showed improvement, a significant difference. Thus, short-term observations suggested that a form of chondroitin sulfate can improve osteoarthritic conditions.

Investigators from the Internal Medicine/Rheumatology Polyclinic of Charles University in Prague, Czechoslovakia conducted independent com-parisons of arteparon and rumalon in osteoarthritis of the knee in long-term studies lasting five and ten years.10 Fifty patients with osteoarthritis of the knee in each of three groups were given either intra-muscuiar injections of vitamin B12 (controls), arteparon (ten courses of injections at six month intervals for a total dose of 7.5 grams), or rumalon (ten courses of injections at six month intervals for a total dose of 250 ml).10 All patients were also given standard analgesics and NSAIDS.

Knee pain was decreased for two years in the control group, but afterwards, became progressively worse, even with higher NSAID doses. This is typical of standard therapy. However, knee pain was decreased quickly (within four months) and to a much greater degree with arteparon and rumalon, along with a decrease in analgesics, and continued to decrease even after five years. Likewise, measures of joint function (time to ascend and descend a 15-step staircase) were maintained for two years in each group, but thereafter, clear divergence was seen. The control group became progressively worse, while the GAG groups became progressively better. Similarly, the ability to work became worse with the control group until, after five years, all controls were unfit for work. Conversely, after five years, between 50 and 80 percent of GAG subjects were fit for work

 

[CYPHON]

Nice! How are u using it? I felt nothing from vioxx

 

[TBrunson]

Thanks for the writeup Tapout1. I've read on other boards the value of Adequan and am anxious to try it on my dog However, to-date I haven't found an online retailer that will ship it without a vet rx. Grrrrrrrr......

Back to google.com

TB.