If it is feasalbe for trt, some wont be ablle to use it due to its psychological side effects. Clomid ripped my head off and shit down my neck. I HATE CLOMID!
Dosxx, my treatment outcome went exactly the same as yous. I do feel a little on edge while on, but my wife is finally pregnant, so i can go on the test shots.
I think it was 50mg day. Sent me into a deep ass depression and pegged my anxiety at the same time. I was fucked up a good two months.please explain, and at what dose?
Im on clomid only hrt 50mg a day.
Crit was good last 2 blood tests, estrogen was high, but now controlled by letro. All is endo prescribed
I think it was 50mg day. Sent me into a deep ass depression and pegged my anxiety at the same time. I was fucked up a good two months.
That's cool bro. I don't mind answering.It's not really my business, but since you volunteered this info, I'm curious why your endo would have you on such an unconventional HRT. Are you achieving target test levels of 550-900? Letro also raises test - why the clomid? (Needless to say, we have very little data on the long-term use of clomid in men. It has both estrogenic and anti-estrogenic properties depending on the tissues.)
Maybe there is a good reason for this regimen. Unless there is something special going on, you might like 100-150 mg of cyp a week (or 1-2 tubes of testim) with a little arimidex for estro control. That's what 99% of endos do for HRT. Some use clomid, nolva, or HCG to keep the balls from experiencing atrophy.
If clomid is working for you, that's great ...
It's not really my business, but since you volunteered this info, I'm curious why your endo would have you on such an unconventional HRT. Are you achieving target test levels of 550-900? Letro also raises test - why the clomid? (Needless to say, we have very little data on the long-term use of clomid in men. It has both estrogenic and anti-estrogenic properties depending on the tissues.)
Maybe there is a good reason for this regimen. Unless there is something special going on, you might like 100-150 mg of cyp a week (or 1-2 tubes of testim) with a little arimidex for estro control. That's what 99% of endos do for HRT. Some use clomid, nolva, or HCG to keep the balls from experiencing atrophy.
If clomid is working for you, that's great ...
Clomiphene Citrate Effects on Testosterone/Estrogen Ratio in Male Hypogonadism
J Sex Med 2005;2:716–721.
ABSTRACT
Aim. Symptomatic late-onset hypogonadism is associated not only with a decline in serum testosterone, but also with a rise in serum estradiol. These endocrine changes negatively affect libido, sexual function, mood, behavior, lean body mass, and bone density. Currently, the most common treatment is exogenous testostosterone therapy. This treatment can be associated with skin irritation, gynecomastia, nipple tenderness, testicular atrophy, and decline in sperm counts. In this study we investigated the efficacy of clomiphene citrate in the treatment of hypogonadism with the objectives of raising endogenous serum testosterone (T) and improving the testosterone/estrogen (T/E) ratio.
Methods. Our cohort consisted of 36 Caucasian men with hypogonadism defined as serum testosterone level less than 300 ng/dL. Each patient was treated with a daily dose of 25 mg clomiphene citrate and followed prospectively. Analysis of baseline and follow-up serum levels of testosterone and estradiol levels were performed.
Results. The mean age was 39 years, and the mean pretreatment testosterone and estrogen levels were 247.6 ± 39.8 ng/dL and 32.3 ± 10.9, respectively. By the first follow-up visit (4–6 weeks), the mean testosterone level rose to 610.0 ± 178.6 ng/dL (P < 0.00001). Moreover, the T/E ratio improved from 8.7 to 14.2 (P < 0.001). There were no side effects reported by the patients.
Conclusions. Low dose clomiphene citrate is effective in elevating serum testosterone levels and improving the testosterone/estadiol ratio in men with hypogonadism. This therapy represents an alternative to testosterone therapy by stimulating the endogenous androgen production pathway.
Int J Androl. 1981 Jun;4(3):372-8.
Clomiphene citrate administration to normogonadotropic subfertile men: blood hormone changes and activation of acid phosphatase in seminal fluid.
Ronnberg L, Vihko P, Sajanti E, Vihko R.
Clomiphene citrate was administered as a 50 mg oral daily dose to 44 normogonadotrophic (serum FSH 2-10 mIU/ml) subfertile men for 3 months. The treatment resulted in significant increases in FSH and LH concentrations, whereas prolactin remained unchanged. Serum testosterone and oestradiol both increased highly significantly. The increased testosterone levels suggest that the elevated LH levels had not led to "down regulation" of Leydig cell LH/hCG receptors, neither had the greatly increased estradiol led to depletion of these receptors. This is suggested to be a result of the blocking of testicular oestradiol receptors by the estrogen antagonist, clomiphene.
That's cool bro. I don't mind answering.
Endo did my full panel, lh, fsh, and test where below normal. Doc said I can go on the shots, until I told him my wife wants a baby. The clomid brought my lh up in turn brought my test levels up to around 800. It also raised my fsh, what signals the gonads to produce sperm. Estro went up with this treatment also, hence why I'm on the letro. No lie to you tho, the clomid can make you a different person emotionally.
Anyways, my wife is now pregnant after 6 months on the clomid, I'm looking forward to being a dad. I'm also looking forward to getting off this clomid, and starting the shots.
There are quite a few studies on the matter and it appears to be supported quite well. Some studies lasted for a year or more with no negative sides upon cessation. Most of the negative sides that bodybuilders experience come from overdosing.