Bolus: A Practical and Research Guide for the Use of recombinant hGH and GH Secretagogues: Status Update; Table of Contents; Monthly Newsletter

[Type-IIx]

Great read and awesome content. In the section in tren you state

"It decreases fat mass and increases skeletal muscle mass by acting analogously to
DHT"

So it acts similar to DHT despite being a 19 nor and not DHT derivative. Could you explain a little more about this, or maybe I am not understanding correctly?

It reads as if something's missing probably because something is. The citation! Which is Gupta, V., Bhasin, S., Guo, W., Singh, R., Miki, R., Chauhan, P., … Jasuja, R. (2008). Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes. Molecular and Cellular Endocrinology, 296(1-2), 32–40. doi:10.1016/j.mce.2008.08.019

That section is informally written so I didn't put in the references or footnotes, but am always happy to give those, and to provide evidence about any factual statements. Basically, DHT – a potent androgen, like Tren; but shitty anabolic unlike Tren – reduces fat mass by "committing preadipocytes to a myogenic rather than adipogenic lineage," i.e., at the pre-translational level Tren, like DHT, tends to build muscle rather than fat with energy – as well as by increased lipolysis, and reduced lipid accumulation.

The "DHT-19-Nor-Test" model is broscience, btw. I've written about this briefly here: [link]

It's a bodybuilding hypothesis, not a scientific framework. It comes from an infographic someone came up with years back. I won't attach it because it'll just contribute to further repetition of errata.

 

[VakarianSK]

It reads as if something's missing probably because something is. The citation! Which is Gupta, V., Bhasin, S., Guo, W., Singh, R., Miki, R., Chauhan, P., … Jasuja, R. (2008). Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes. Molecular and Cellular Endocrinology, 296(1-2), 32–40. doi:10.1016/j.mce.2008.08.019

That section is informally written so I didn't put in the references or footnotes, but am always happy to give those, and to provide evidence about any factual statements. Basically, DHT – a potent androgen, like Tren; but shitty anabolic unlike Tren – reduces fat mass by "committing preadipocytes to a myogenic rather than adipogenic lineage," i.e., at the pre-translational level Tren, like DHT, tends to build muscle rather than fat with energy – as well as by increased lipolysis, and reduced lipid accumulation.

The "DHT-19-Nor-Test" model is broscience, btw. I've written about this briefly here: [link]

It's a bodybuilding hypothesis, not a scientific framework. It comes from an infographic someone came up with years back. I won't attach it because it'll just contribute to further repetition of errata.

So your saying that there is no such thing as 19-nor based compound and DHT derivitive compound categroies? Or are you saying it is just a bad way to group AAS but that the 19-nor based compounds and DHT derivitive compounds are still valid categories?

 

[Type-IIx]

So your saying that there is no such thing as 19-nor based compound and DHT derivitive compound categroies? Or are you saying it is just a bad way to group AAS but that the 19-nor based compounds and DHT derivitive compounds are still valid categories?

What is it with this, exclusively ProM, tendency for people to try to walk me into giving them the answer that they wish to hear? This tactic is not something I've experienced elsewhere since I made the mistake of dating a chick with borderline personality disorder in undergrad.

 

[VakarianSK]

What is it with this, exclusively ProM, tendency for people to try to walk me into giving them the answer that they wish to hear? This tactic is not something I've experienced elsewhere since I made the mistake of dating a chick with borderline personality disorder in undergrad.

?
This was a genuine question not a "trying to bait you" question.

 

[Reno911]

?
This was a genuine question not a "trying to bait you" question.

Do not question anything or you will feel his wrath!!! (I made the mistake and needed therapy to work through it).

 

[bbxtreme]

?
This was a genuine question not a "trying to bait you" question.

In all fairness I understood what he was saying in his post. But I can see how it may be confusing.

1. DHT is not tren and makes a shitty anabolic and doesn’t have the properties.

2. It’s a bit more complex than to just say something is a DHT based compound and there’s a lot of bro science involved in that.

I haven’t read his full articles yet, but that’s what I took away from the above- he can correct me if I am wrong.

But I do agree it’s a bit more complex than that. Dr. Dean and some others have done some presentations around this as well.

Sometimes it’s just hard to put this stuff in layman’s terms.

 

[Type-IIx]

@VakarianSK I read your question as thoroughly loaded. With that said, I know you're a good dude and welcome you to the Discord. I believe you'll be a great addition! I just can't be arsed to answer these sorts of questions.

 

[VakarianSK]

@VakarianSK I read your question as thoroughly loaded. With that said, I know you're a good dude and welcome you to the Discord. I believe you'll be a great addition! I just can't be arsed to answer these sorts of questions.

No problem and I understand, your a busy guy.

 

[Type-IIx]

Great to chat with you today, @VakarianSK. Hope you can make it, < 1 hr

 

[Type-IIx]

VITAL UPDATE (GOOD NEWS)

My illustrator has finished her work (this book is going to look fucking awesome) and my developer his so that books can actually start shipping from Ampouletude: Home of Type-IIx

All that's left now is for me to arrange it, send some preprints to colleagues and to an editor for review, and then, START SHIPPING!

I promise to let everyone know by creating a thread here when it's shipping!

Thank you all for your strong interest; seriously!

Here is the Table of Contents from Bolus: A Practical and Reference Guide for the Use of recombinant hGH and GH Secretagogues: [link]

 

[Type-IIx]

Teaser: