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BPC-157 and HGH

Viking55

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Jan 16, 2010
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Aloha,

Is there a recommended/suggested time between BPC-157 injections and injecting HGH?

Mahalo nui loa,
V
 

johnjuanb1

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Aloha,

Is there a recommended/suggested time between BPC-157 injections and injecting HGH?

Mahalo nui loa,
V

One study suggests BPC-157 makes HGH possibly more anabolic so i used to take the BPC-157 with GHRP2/cjc no DAC, wait 10 minutes then take HGH.
 

johnjuanb1

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Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts.
Chang CH, et al. Molecules. 2014.

Abstract

BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon in many animal studies. However, the underlying mechanism has not been fully clarified. The present study aimed to explore the effect of BPC 157 on tendon fibroblasts isolated from Achilles tendon of male Sprague-Dawley rat. From the result of cDNA microarray analysis, growth hormone receptor was revealed as one of the most abundantly up-regulated genes in tendon fibroblasts by BPC 157. BPC 157 dose- and time-dependently increased the expression of growth hormone receptor in tendon fibroblasts at both the mRNA and protein levels as measured by RT/real-time PCR and Western blot, respectively. The addition of growth hormone to BPC 157-treated tendon fibroblasts dose- and time-dependently increased the cell proliferation as determined by MTT assay and PCNA expression by RT/real-time PCR. Janus kinase 2, the downstream signal pathway of growth hormone receptor, was activated time-dependently by stimulating the BPC 157-treated tendon fibroblasts with growth hormone. In conclusion, the BPC 157-induced increase of growth hormone receptor in tendon fibroblasts may potentiate the proliferation-promoting effect of growth hormone and contribute to the healing of tendon.
 

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