ghrp-6 receptor

[muscle69]

Is ghrp-6 receptor like a higher purity peptide??

 

[muscle69]

bump!

 

[DatBtrue]

There is no GHRP-6 receptor.

There is a receptor to which all the GHRPs (GHRP-6, GHRP-2, Ipamorelin & Hexarelin) bind to. That was called The Growth Hormone Secretagogue Receptor (GHS-R).

Those GHRPs I just named are artificial constructs of what was eventually discovered naturally as Ghrelin. Those GHRPs have the GH releasing characteristics of Ghrelin w/o the fat accumulating effect.

Today the GHS-R is often called the Ghrelin Receptor. There are two variants of this receptor GHSR1(a) & GHSR1(b) and not a lot is known about the second variant.

Here is a good description for you. From the IUPHAR RECEPTOR DATABASE

"The ghrelin receptor, previously designated as an orphan G protein-coupled receptor, was cloned by Howard et al. in 1996 from the pituitary and hypothalamus of humans and swine [1]. It was shown to be the target of growth hormone secretagogues, a class of synthetic peptide and non-peptide compounds that stimulate growth hormone (GH) release from the anterior pituitary. Nucleotide sequence analysis revealed 2 types of cDNAs, apparently splice variants of the same gene, that are referred to as GHSR1(a) and GHSR1(b) [1]. The human full-length type, GHSR1(a) cDNA encodes a predicted polypeptide of 366 amino acids with 7 transmembrane domains and is the subject of this review. GHSR1(b) is predicted to encode a truncated polypeptide of 289 amino acids with only 5 transmembrane (1-5) domains. The function, if any, is not yet known."​

So to answer your question the receptors are made up of an amino acid chain or polypeptide.

 

[muscle69]

There is no GHRP-6 receptor.

There is a receptor to which all the GHRPs (GHRP-6, GHRP-2, Ipamorelin & Hexarelin) bind to. That was called The Growth Hormone Secretagogue Receptor (GHS-R).

Those GHRPs I just named are artificial constructs of what was eventually discovered naturally as Ghrelin. Those GHRPs have the GH releasing characteristics of Ghrelin w/o the fat accumulating effect.

Today the GHS-R is often called the Ghrelin Receptor. There are two variants of this receptor GHSR1(a) & GHSR1(b) and not a lot is known about the second variant.

Here is a good description for you. From the IUPHAR RECEPTOR DATABASE

"The ghrelin receptor, previously designated as an orphan G protein-coupled receptor, was cloned by Howard et al. in 1996 from the pituitary and hypothalamus of humans and swine [1]. It was shown to be the target of growth hormone secretagogues, a class of synthetic peptide and non-peptide compounds that stimulate growth hormone (GH) release from the anterior pituitary. Nucleotide sequence analysis revealed 2 types of cDNAs, apparently splice variants of the same gene, that are referred to as GHSR1(a) and GHSR1(b) [1]. The human full-length type, GHSR1(a) cDNA encodes a predicted polypeptide of 366 amino acids with 7 transmembrane domains and is the subject of this review. GHSR1(b) is predicted to encode a truncated polypeptide of 289 amino acids with only 5 transmembrane (1-5) domains. The function, if any, is not yet known."​

So to answer your question the receptors are made up of an amino acid chain or polypeptide.

thank you DatBtrue.......I appreciate that info!!