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Hairloss and Testosterone?

BigMatt

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Ive read several studies that contradict itself on Hairloss Vs Testosterone.

Several of those studies state that Hairloss is in Fact a LOSS of Testosterone and not and overproduction of Testosterone.

From real life examples.

Ive had several friends that Loss their hair Once they got married and Had Childrens with their wife.

Marriage is known to lower testosterone levels.

Studies state that this is a loss of testosterone not a gain.

It kinda make sense, Since high testosterone levels are the highest between 18 to 25 years old. When you get older 30+ Some start to lose their hair.

Some claim that Losing hair is because of High Testosterone, but These are fewer.

What do you guys think?
 

Winston84

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Start running steroid cycles and if you are predisposed to hair loss it will accelerate, same with prostate enlargement, liver problems and heart enlargement.
 

Bio

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Please post up some studies (Links).
 

BigMatt

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A low testosterone actually creates high DHT levels ("to cover up those loses")

LOW TESTOSTERONE LEVELS can accelerate hair loss because your body make more DHT to compensate for missing Testosterone !

ive read this on several websites.


It kinda make sense.
 
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LATS

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Estrogen in men has been theorized to cause HAIRLOSS in men as well.. As we get older we convert more test to estro.. .. So that may be the culprit also..
 

b_cornelius

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So you're saying it's More-or-Less about More or Less

Yah Testosterone potentiates the rate of protein synthesis. Hair is protein and grows faster with more Testosterone. It's just a matter of flow, if everything can keep up. Sort of the logistics of everything, similar to the idea of toxicity.
 

natrol

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A low testosterone actually creates high DHT levels ("to cover up those loses")

LOW TESTOSTERONE LEVELS can accelerate hair loss because your body make more DHT to compensate for missing Testosterone !

ive read this on several websites.


It kinda make sense.
Testosterone converts into DHT. DHT is what is responsible for accelerating male pattern baldness. This is why steroids accelerate hair loss, literally because increased levels of androgens/DHT expedite male pattern baldness progression. With your theory, you're saying we should all be on a gram test to keep our hair.

Low test does not accelerate hair loss, higher test does.

When you get older and your testosterone levels decline, you don't make more DHT, the levels remain constant.

As men’s testosterone levels decline, their bodies also begin shifting the conversion of free testosterone toward DHT and away from other testosterone byproducts. This is how serum (blood) DHT levels remain constant, even when men’s testosterone levels plummet.

https://academic.oup.com/jcem/article-lookup/doi/10.1210/jcem.87.2.8201

Supraphysiological levels of test = greater rate of hair loss if prone to MPB (because of heightened DHT levels)
Normal levels of test = whatever rate you're genetically prone to, but not accelerated
Low levels of test = whatever rate you're genetically prone to, but not accelerated

The reason you don't see hair loss in young guys is because hair loss isn't an overnight process. Typically, most guys don't even notice they are losing hair until they've permanently lost 1/3 or more of the hair on their head. I know I ran several cycles and shed thousands of hairs before I noticed my diffuse thinning was getting really bad.

You only have a certain amount of hair on your head, and each year you progress closer to your ultimate final inevitable fate, and the rate at which you get there is determined by your genetics, and largely by how much DHT is in your body and how sensitive your hair follicles are to that DHT (genetic).
 
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Chemyo

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Nobody knows. One possibility is that a developmental switch, independent of androgen exposure, changes gene expression, splicing patterns, and so on in hair follicle cells. Then when present, androgens trigger the miniaturization of the HF through interaction of AR (which may itself have higher expression) with these other factors.

Another possibility or co-factor is that there are many studies out there that oxidative stress/ROS plays an important role in AGA (downstream of T > DHT > AR of course). As we get older anti-oxidant defenses get lowered and cells get stressed out more easily.

Estrogen in men has been theorized to cause HAIRLOSS in men as well.. As we get older we convert more test to estro.. .. So that may be the culprit also..
Absolutely not. E2 is beneficial. Observations prove this. Eg studies and case reports of transgenders where men become women show that under influence of anti-androgen therapy and E2 supplementation those people can regrow big amounts of hair, even in total bald areas.

Secondly, raw observations show the same in women. Women can start having troubles with hair loss after the menopause period which is characterized by a decrease in estrogen production. Women who take aromatase inhibitors may start to lose their hair too.

Then you have PCOS...

Lastly and most importantly, when we look at people who have androgen insensitivity syndrome or 5ar2 deficiency, they simply pretty much never have hair quality issues.

Also what is interesting is that when you look at occipital non balding and balding scalp of Androgenetic Alopecia men you can see that the hair follicles in occipital has less androgen receptor expression and more estrogen receptor expression of both ERa and ERb.

This is totally contra to what is seen in the scalp follicles residing in the balding region namely higher AR expression and less expression of both ERa and ERb. Also, aromatase is higher expressed in the occipital region than the frontal region.

To identify differences in the transcription of AR in defined two sites, their mRNA levels were examined. In all samples, mean mRNAs of AR were 3.4- fold higher in VERTEXDPCs than those from occipital scalp (Fig. 1A). These site-specific different expressions of AR were consistent in Western blot (Fig. 1B). VERTEXDPCs showed 1.9-fold higher AR expression than their counterparts, consistent with the results of cultured DPCs from hair follicles from the frontal and occipital scalp [2]. Immunohistochemical study showed that AR was localized to the nuclei of the VERTEXDPCs at the anagen stage (six of eight samples), although not all the DPCs were positive (Fig. 1C). In sebaceous gland, AR immunoreactivity was mostly confined to the nuclei of the basal cells as previously described (Fig. 1D) [4].

Reversely, ERa mRNA expression levels were 2.2- fold higher in OCCIPUTDPCs than in their counterparts. ERb mRNA was consistently highly expressed by 4.2- fold in OCCIPUTDPCs versus VERTEXDPCs (Fig. 2A). ERa protein was consistently elevated in OCCIPUTDPCs by 1.8-fold higher versus vertex and ERb was also definitely increased in DPCs from non-balding scalps, with a 1.8-fold stronger intensity (Fig. 2B).
 
Last edited:

BigMatt

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Testosterone converts into DHT. DHT is what is responsible for accelerating male pattern baldness. This is why steroids accelerate hair loss, literally because increased levels of androgens/DHT expedite male pattern baldness progression. With your theory, you're saying we should all be on a gram test to keep our hair.

Low test does not accelerate hair loss, higher test does.

When you get older and your testosterone levels decline, you don't make more DHT, the levels remain constant.

As men’s testosterone levels decline, their bodies also begin shifting the conversion of free testosterone toward DHT and away from other testosterone byproducts. This is how serum (blood) DHT levels remain constant, even when men’s testosterone levels plummet.

https://academic.oup.com/jcem/article-lookup/doi/10.1210/jcem.87.2.8201

Supraphysiological levels of test = greater rate of hair loss if prone to MPB (because of heightened DHT levels)
Normal levels of test = whatever rate you're genetically prone to, but not accelerated
Low levels of test = whatever rate you're genetically prone to, but not accelerated

The reason you don't see hair loss in young guys is because hair loss isn't an overnight process. Typically, most guys don't even notice they are losing hair until they've permanently lost 1/3 or more of the hair on their head. I know I ran several cycles and shed thousands of hairs before I noticed my diffuse thinning was getting really bad.

You only have a certain amount of hair on your head, and each year you progress closer to your ultimate final inevitable fate, and the rate at which you get there is determined by your genetics, and largely by how much DHT is in your body and how sensitive your hair follicles are to that DHT (genetic).
This is totally false.

A shitload of Old guys have prostate problems because of DHT levels increasing as they get older.

Alot of guys who take dht derivatives(Winstrol,Masteron) Lose all their hairs.
 
Last edited:

Chemyo

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This is totally false.

A shitload of Old guys have prostate problems because of DHT levels increasing as they get older.

Alot of guys who take dht derivatives(Winstrol,Masteron) Lose all their hairs.
Where have you read that DHT levels increase as men get older? AFAIK most studies have either noted no significant decline until very old age, or a decline, but certainly not increasing DHT levels with age:

1. D. Drafta, A.E. Schindler, E. Stroe, E. Neacs¸ u, Age-related changes of
plasma steroids in normal adult males, J. Steroid Biochem. 17 (6) (1982)
683–687

2. G. Giusti, P. Gonnelli, D. Borrelli, G. Fiorelli, G. Forti, M. Pazzagli, M. Serio, Agerelated
secretion of androstenedione, testosterone and dihydrotestosterone by
the human testis, Exp. Gerontol. 10 (5) (1975) 241–245

3. R. Ghanadian, C.M. Puah, Age-related changes of serum 5alpha-androstane-
3alpha, 17beta-diol in normal men, Gerontology 27 (5) (1981) 281–285

4. K.M. Pirke, P. Doerr, Age related changes in free plasma testosterone, dihydrotestosterone
and oestradiol, Acta Endocrinol. (Copenh.) 80 (1) (1975)
171–178.

5. P.Y. Liu, J. Beilin, C. Meier, T.V. Nguyen, J.R. Center, P.J. Leedman, M.J. Seibel, J.A.
Eisman, D.J. Handelsman, Age-related changes in serum testosterone and sex hormone binding globulin in Australian men: longitudinal analyses of two geographically
separate regional cohorts, J. Clin. Endocrinol. Metab. 92 (9) (2007)
3599–3603

6. Stárka L1, Pospísilová H, Hill M. J, Free testosterone and free dihydrotestosterone throughout the life span of men.
Steroid Biochem Mol Biol. 2009 Aug;116(1-2)
 
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LATS

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Last edited:

alfresco

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well . . .

Male castration results in zero hair loss or the cessation of male-pattern hair loss (MPHL).
It also results in zero testosterone.

The correlation between testosterone and hair loss was first observed in eunuchs and
the castrato singers.

There is no cure for MPHL, technically called androgenetic alopecia. If there was, there
would be no bald men.
 

natrol

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This is totally false.

A shitload of Old guys have prostate problems because of DHT levels increasing as they get older.

Alot of guys who take dht derivatives(Winstrol,Masteron) Lose all their hairs.
I literally posted a study in my post that shows that DHT levels do not increase when men age and their test levels decline, rather, their DHT levels remain constant.

Yes, guys who take DHT derivatives who are prone to MPB lose their hair quicker, because they are introducing more DHT into their systems. I literally stated that in my post as well. Heightened DHT = accelerated male patten baldness if genetically prone

What I'm saying (and already did quite sufficiently I believe) is that your DHT levels don't increase when your test levels decline, they stay constant, which answers your original question about low test resulting in an expedited level of hair loss progression.

Supraphysiological levels of test = greater rate of hair loss if prone to MPB (because of heightened DHT levels)
Normal levels of test = whatever rate you're genetically prone to, but not accelerated
Low levels of test = whatever rate you're genetically prone to, but not accelerated

If you ask for our opinions, don't give us shit when we have a different opinion than you.

Believe whatever you want to believe.
 
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BigMatt

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William Wong, Estrogen and Hair Loss.... This amongst numerous other sites etc show that many in the " HAIRLOSS world " are starting to think its the imbalance between estro and test in men.. Google " estrogen related hairloss in men " and look at the other sites as well.. Not saying he is right but low testosterone has been related to hairloss as well..Estrogen and Hair Loss - How to Stop the Shedding!..
This make sense.

I know alot of Bald guys with Bitch tits and they act like fucking women.

Their bodyshape start to look like women. they get fatter in the hips and chest area.
 

BigMatt

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Male castration results in zero hair loss or the cessation of male-pattern hair loss (MPHL).
It also results in zero testosterone.

The correlation between testosterone and hair loss was first observed in eunuchs and
the castrato singers.

There is no cure for MPHL, technically called androgenetic alopecia. If there was, there
would be no bald men.
You can manipulate hormone levels tru Diet.

Staying lean is one part.
 

LEX

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This make sense.

I know alot of Bald guys with Bitch tits and they act like fucking women.

Their bodyshape start to look like women. they get fatter in the hips and chest area.
Tranny's on female hormones don't loose their hair typically
 

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