IGF-1 LR3 verses PEG-MGF

[Lethal Threath]

Have never tried any of them.
Wich one would you choose and why?

 

[johnjuanb1]

Definitely IGF-1(LR3)

I love IGF-1(LR3). Been on peptides for 3 1/2 weeks. GHRP-6/CJC-1295(without DAC) the whole time. Used IGF-1(LR3) 100mcg pwo 5x/week for 2 weeks. Pumps were insane! Bodyweight went from 214LBS to 231LBS in 2 weeks. Never have been so full! Felt like when I took 8iu serostim/day. The past week and a half I've replaced the IGF-1(LR3) with 400mcg PEG MGF, 2 hours prior to workout, IM bilateral in muscle worked, every other day. Pumps are pretty good. I think the pumps are from the GHRP-6/CJC-1295, not the PEG MGF. My weight has increased from 231LBS to 235LBS. The feeling on IGF-1(LR3) is like nothing I've ever felt in 21 years of bodybuilding. It took my physic to another level. Going back on the IGF-1(LR3) next week. Going to try using it 3x/week in divided doses 3x/day at 20mcg upon waking, followed by 10iu humulin-h 20 min later, same protocol in the afternoon,
and 40mcg pwo, followed by humulin-h 20 min later. I wanna see if divided doses and 3x/week prevents receptor downregulation and oversaturation.

 

[0o0o0o]

I love IGF-1(LR3). Been on peptides for 3 1/2 weeks. GHRP-6/CJC-1295(without DAC) the whole time. Used IGF-1(LR3) 100mcg pwo 5x/week for 2 weeks. Pumps were insane! Bodyweight went from 214LBS to 231LBS in 2 weeks. Never have been so full! Felt like when I took 8iu serostim/day. The past week and a half I've replaced the IGF-1(LR3) with 400mcg PEG MGF, 2 hours prior to workout, IM bilateral in muscle worked, every other day. Pumps are pretty good. I think the pumps are from the GHRP-6/CJC-1295, not the PEG MGF. My weight has increased from 231LBS to 235LBS. The feeling on IGF-1(LR3) is like nothing I've ever felt in 21 years of bodybuilding. It took my physic to another level. Going back on the IGF-1(LR3) next week. Going to try using it 3x/week in divided doses 3x/day at 20mcg upon waking, followed by 10iu humulin-h 20 min later, same protocol in the afternoon,
and 40mcg pwo, followed by humulin-h 20 min later. I wanna see if divided doses and 3x/week prevents receptor downregulation and oversaturation.

has anyone seen results like these!?

 

[123cctv]

has anyone seen results like these!?

Yes, those results sound typical.

 

[qwerty]

I love IGF-1(LR3). Been on peptides for 3 1/2 weeks. GHRP-6/CJC-1295(without DAC) the whole time. Used IGF-1(LR3) 100mcg pwo 5x/week for 2 weeks. Pumps were insane! Bodyweight went from 214LBS to 231LBS in 2 weeks. Never have been so full! Felt like when I took 8iu serostim/day. The past week and a half I've replaced the IGF-1(LR3) with 400mcg PEG MGF, 2 hours prior to workout, IM bilateral in muscle worked, every other day. Pumps are pretty good. I think the pumps are from the GHRP-6/CJC-1295, not the PEG MGF. My weight has increased from 231LBS to 235LBS. The feeling on IGF-1(LR3) is like nothing I've ever felt in 21 years of bodybuilding. It took my physic to another level. Going back on the IGF-1(LR3) next week. Going to try using it 3x/week in divided doses 3x/day at 20mcg upon waking, followed by 10iu humulin-h 20 min later, same protocol in the afternoon,
and 40mcg pwo, followed by humulin-h 20 min later. I wanna see if divided doses and 3x/week prevents receptor downregulation and oversaturation.

What was your timing between the cjc/ghrp inject and the igf?

 

[johnjuanb1]

timing of inject

I would take my igf-1(lr3) immediately p.w. at around 7pm. I would wait to feel somewhat hypoglycemic, about a half hour, then have a protein drink, followed by a high carb/high protein dinner. Finish eating by 8pm. No food for 2 hours. Then I would take my ghrp-6/cjc-1295(without DAC) at 10pm. There was a 3 hour time period between my igf-1(LR3) inject and my ghrp-6/cjc-1295 inject. I also take ghrp-6/cjc-1295 at around 1am, when i get up to go to the bathroom, upon waking, and when I get home from work at 3pm. My 10pm and 1 am injects are each coupled with 12mg melatonin. Just started doing that this week. Supposed to double the gh output.

 

[DatBtrue]

Have never tried any of them.
Wich one would you choose and why?

Neither.

 

[BadGenCD]

Dat, you a fan of just straight GH or GHRP+GHRH right?

 

[DatBtrue]

Dat, you a fan of just straight GH or GHRP+GHRH right?

Yes or even GH + GHRP/GHRH in some situations.

See my post: Post #480

"Treatment with rhGH alone lead to an increase in IGF-IEa [muscle IGF-1] and MGF of about 3 fold over control (Table 1). However, treatment with IGF-I abolished expression of both isoforms. When used in combination, the inhibitory effect of IGF-I overode the GH stimulation of IGF-IEa and MGF transcription. "

 

[Lorken]

Interesting dat. So you don't think LR3 or PEG-MGF do anything?

How would you explain the gains I've read so much about?

I was thinking of using LR3/PEG-MGF for a PCT, but maybe I'll just do CJC-1259(w/dac), and GHRP-6, with maybe some GH (2-4ui/day).

 

[bigdozzer]

its hard to find real igf but if you can it is much better

 

[DatBtrue]

Interesting dat. So you don't think LR3 or PEG-MGF do anything?

I didn't say that. I have discussed these things throughout my thread... to the point where I am tired of discussing it.

And I posted and pondered and posted in such a way that nobody has to completely rely on me.

Concerning Peg-MGF my opinion is best expressed here: http://www.professionalmuscle.com/forums/showthread.php?p=514207#post514207

...with a more detailed explanation on how it works here: http://www.professionalmuscle.com/forums/showthread.php?p=487161#post487161

How would you explain the gains I've read so much about?

Again I did not say that IGF-1 LR3 would be without effect. I know that it has a lower binding affinity then regular IGF-1 for the IGF-1 receptor. I know that it will travel systemically and not be confined to the area injected. To be confined to the area injected it would need to be a molecule of a weight sufficient to disallow penetration of the vascular wall. However it is small enough to pass through the vascular wall and into the bloodstream.

In order to be large enough to be confined (i.e. incapable of penetrating a blood vessel) it would need to be xxx kdaltons in weight. The ternary complex is large enough to be confined. IGF-1 LR3 is incapable of forming such a complex. IGF-1 prebound to IGFBP3 when it is injected quickly binds to Acid Labile Subunit and should be confined to the general area.

See for example: http://www.professionalmuscle.com/forums/showthread.php?p=496050#post496050

So using a large dose may work.

But injecting any IGF-1 or MGF (which acts as IGF-1) post workout is likely the wrong time to administer it.

See: http://www.professionalmuscle.com/forums/showthread.php?p=532884#post532884

You don't need huge amounts for wounds and for a positive effect in PCT but for anabolism you do.

IGF-1 it is a very solid contributor to the healing process. When people inject it near wounds they get very good healing effects.

So how can we reconcile the apparent discrepancy?

Easily...the dose of IGF-1 necessary to produce a systemic anabolic action is 500 times higher then that necessary to produce a therapeutic effect (300 ng versus 160 mg).

So if an IGF-1 LR3 administration is 500 times less sufficient then it needs to be to be anabolic it will still be therapeutic if it can be delivered near the site of injury.

But really the key to understanding things is to understand what GH & IGF-1 do and do not do. See: http://www.professionalmuscle.com/forums/showpost.php?p=542685&postcount=864

I was thinking of using LR3/PEG-MGF for a PCT, but maybe I'll just do CJC-1259(w/dac), and GHRP-6, with maybe some GH (2-4ui/day).

In my opinion all of them will work as will insulin in helping to restore the PCT.

You will also notice that a vast number of people who claim big benefit from IGF-1 are unfamiliar with insulin & glucose disposal. It is easy to be excited and benefit from increased glucose disposal.

As for genuine muscle building... do I believe some people have benefited. Sure. Why not?

 

[Lorken]

I didn't say that. I have discussed these things throughout my thread... to the point where I am tired of discussing it.

You mean the one titled "...CJC-1259 GHRP-6..."?

Wow, you need an e-book, or at least all of this stuff organized, and not in a seemingly random order. I hope you have all this stuff saved somewhere. It'd be a shame if it was all lost.

Anyway, thanks for clearing that up.