It's HCG time again - Question

[Coopie]

Question for y'all...

When doing HCG, do you go with IM or SubQ?

I've done both in the past, but since I've been hitting my IM sweet-spots so often, I think I might run the HCG SubQ this time around. I have found IM HCG to sometimes "irritate" the muscle, making subsequent shots painful.

Throw out your thoughts...

Thanks.

 

[drgoodbody]

IM has been shown to be more bioavailable - and I've always used it that way with no issues. Can inject it either way tho, sub-q or IM.

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Bioavailability of HCG after intramuscular or subcutaneous injection in obese and non-obese women.

Chan CC, Ng EH, Chan MM, Tang OS, Lau EY, Yeung WS, Ho PC.

Department of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, SAR, China. [email protected]

BACKGROUND: Obese women require higher gonadotrophin doses for ovarian stimulation and to trigger ovulation. The bioavailability of a drug is affected by its route of administration. Herein, the bioavailability of hCG was compared after intramuscular (i.m.) or subcutaneous (s.c.) injection in obese and non-obese women. METHODS: Twenty four Chinese women, 12 with a body mass index (BMI) 28 kg/m(2) and 12 with a BMI of 20-25 kg/m(2) were recruited as the obese and non-obese groups respectively. A single hCG injection was given intramuscularly on one occasion, and subcutaneously on a second occasion, separated by 4 weeks. Blood samples were taken at intervals for the pharmacokinetic study of hCG. RESULTS: Examination of the hCG plasma concentration-time curve showed the area under the curve (AUC) and maximum concentration (C(max)) of hCG to be significantly higher after i.m. injection than after s.c. injection in both the obese and non-obese groups. However, the AUC and C(max) values in obese women were significantly lower than in non-obese women, irrespective of whether i.m. or s.c. dosing was employed. CONCLUSIONS: Intramuscular dosing of hCG provided better bioavailability than s.c. dosing , but bioavailability was significantly less in obese women than in non-obese women
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DrG

 

[Coopie]

Awesome info! Thanks!

Now all I need is an obese Chinese woman to inject!

 

[bigbaldbulldog]

Awesome info! Thanks!

Now all I need is an obese Chinese woman to inject!

I have injected a few myself and i hardly felt a thing..lmao... ..

I have found a few shots over the years to feel like a bee sting...i just went to the triceps or delts for all my HCG shots and when all else fails go to the glute with your insulin bro,you get all the sub-q you want there..

 

[Coopie]

BBB -

You're right and I do the same thing. I used Winny in my outer Tri head for a while since it gave me a bee-sting when shot into the butt!

BTW, when you find that obese woman give me a call and we'll tag team her!

 

[bigbaldbulldog]

BBB -

You're right and I do the same thing. I used Winny in my outer Tri head for a while since it gave me a bee-sting when shot into the butt!

BTW, when you find that obese woman give me a call and we'll tag team her!

She was a mail order bride..things went great till she learned english and now i have not seen her in 3 years..lol...

 

[diskey]

I've seen several orginal hcg directions for use papers where it's written that is shall be injected IM, so with IM your suresafe