long r3 igf1 and cancer

[mr.lean]

what are the odds of getting cancer from igf1? is it high? i cant find many reports or cases yet i did find a few. so cancer is a side effect but iif used in extended periods of time? or can you develop cancer after a single dose? any info would be great thank you

 

[DatBtrue]

what are the odds of getting cancer from igf1? is it high? i cant find many reports or cases yet i did find a few. so cancer is a side effect but iif used in extended periods of time? or can you develop cancer after a single dose? any info would be great thank you

I encourage you to read the following post to get a solid understanding A complete understanding of IGF-1 & its potential influence on cancer & longevity

 

[charlesmhlai]

Let's make it simple, it does not cause cancer, rather it promotes the growth and speeds up cancer cells that already exist in the body is one of the pieces of info i have read.

but some claims that cancer cells are already producing enough igf-1 within itself and external igf-1 does not affect it, but some also argued that since cancer cells are always hungry for igf-1, external or not it will try and grab any free running of igf-1 within the body, therefore it;s always best to keep dosage at around 40mcg - 50 mcg, to minimize free flowing of unabsorbed igf-1.

 

[abolish the weak]

I'm a firm believer that using IGF-1 or GH in moderate-large doses for long periods of time, most definitely speeds up the growth of cancer cells.

 

[BadGenCD]

Comments like this suggest a fundamental lack of understanding of cancer and mutagenesis. Cancer is not black and white. Cells are constantly getting mutations due to various factors such as simple errors in replication to environmental mutagens, carcinogens, and free radicals. These errors in DNA replication can build up, over time, to produce cancer. This process can take a VERY VERY long time, and the presence of IGF regulates how quickly cells divide (probability of errors increases with more division) and how often they self destruct (apoptosis). Normally, cells will self destruct when they detect DNA errors, but with excess IGF, the cell cycle does not arrest like it should, and it often replicates when it shouldn't. This is how cancer it "created" by IGF...but you can think of it more like IGF promoting cancer. Obviously LR3 IGF would be worse of a culprit than GH or GHRH for example, b/c the former is unregulated by binding proteins. I would not recommend anyone use LR3 for extended periods or for purposes other than healing injuries in low doses (<20mcg per day). GH seems to have less of an effect on cancer promotion, but I would suspect still would increase likelihood.

Let's make it simple, it does not cause cancer, rather it promotes the growth and speeds up cancer cells that already exist in the body is one of the pieces of info i have read.

but some claims that cancer cells are already producing enough igf-1 within itself and external igf-1 does not affect it, but some also argued that since cancer cells are always hungry for igf-1, external or not it will try and grab any free running of igf-1 within the body, therefore it;s always best to keep dosage at around 40mcg - 50 mcg, to minimize free flowing of unabsorbed igf-1.

 

[charlesmhlai]

Comments like this suggest a fundamental lack of understanding of cancer and mutagenesis. Cancer is not black and white. Cells are constantly getting mutations due to various factors such as simple errors in replication to environmental mutagens, carcinogens, and free radicals. These errors in DNA replication can build up, over time, to produce cancer. This process can take a VERY VERY long time, and the presence of IGF regulates how quickly cells divide (probability of errors increases with more division) and how often they self destruct (apoptosis). Normally, cells will self destruct when they detect DNA errors, but with excess IGF, the cell cycle does not arrest like it should, and it often replicates when it shouldn't. This is how cancer it "created" by IGF...but you can think of it more like IGF promoting cancer. Obviously LR3 IGF would be worse of a culprit than GH or GHRH for example, b/c the former is unregulated by binding proteins. I would not recommend anyone use LR3 for extended periods or for purposes other than healing injuries in low doses (<20mcg per day). GH seems to have less of an effect on cancer promotion, but I would suspect still would increase likelihood.

thank you for the educated info...
however to create something it starts from zero, is my understanding, so please correct me if Im wrong on this.

So yes I agree with IGF-1 being able to replicate damaged cells within our body.

But somehow if there were no dead cells to start with to mutate, then my understanding is that IGF-1 does not "create" / cause cancer, since the person is pre-disposed to having cancer cells within the body already.

Please dun get me wrong my friend, i do agree with what you're saying and yes i am not able to put it into a more scientific tone like you have for us, im not educated towards the science aspect but on the economical respect towards my career... but thank you very much for clarifying it for me.

 

[BadGenCD]

Yea i mean...it depends on your definition of cancer. A since mutation or two is NOT cancer. This happens to cells all the time. IGF can opportunistically make these normally benign events build up over time and become cancer. So your saying it does not "cause" cancer b/c it doesn't cause the initial mutation is quite simple minded.

 

[charlesmhlai]

Yea i mean...it depends on your definition of cancer. A since mutation or two is NOT cancer. This happens to cells all the time. IGF can opportunistically make these normally benign events build up over time and become cancer. So your saying it does not "cause" cancer b/c it doesn't cause the initial mutation is quite simple minded.

well in that case, thanks for sharing ur thoughts, since different choice of words means so much to you as to go into insults...

you believe in such happening is the cause of cancer, and i belive igf-1 cannot "create" cancer...

i respect your opinion... thx for ur valuable thoughts...

 

[BadGenCD]

That wasn't an insult. I didn't say you were simple minded. I said the way you're thinking about this subject is simple minded. Relax bro

 

[charlesmhlai]

That wasn't an insult. I didn't say you were simple minded. I said the way you're thinking about this subject is simple minded. Relax bro

no harms done, either way i learn something new from everybody here, which also includes from your opinion sir...