interpretation:
http://www.professionalmuscle.com/forums/articles-forum/1193-glucophage-metformin-info.html
http://www.professionalmuscle.com/f...-experienced-users-metformin-berberine-2.html
Points to remember:
-blocks some carbs in stomach if taken before meals.
-inhibits liver from making glucose.
-This results in less insulin day in day out and that will increase your sensitivity to it.
"your pancreas releases less insulin compared to you not taking it. IMO its stronger then everything else and I think stays in system longer.
I could be missing something here but when i run slin, I am off Metformin and don't take any type of GDA. To me it would seem to complicate how I have discovered how to use insulin and not get freaking fat."
"Talking to diabetics maybe not the best info unless they are bodybuilders too and eating clean. The ones I know are eating carbs and chasing their blood sugar all day with insulin. Also if you produce zero insulin then again that is a different boat then what we are doing. IF you are diabetic and eating carbs yea I would assume you are taking met at the same time to inhibit some digestion and then of course they will have to manually adjust glucose levels after the meal. Without met they would be using more insulin to do that I would assume so how would that apply to us?"
"Metformin reduces blood glucose levels primarily by suppressing glucose formation in the liver (hepatic gluconeogenesis).59"
"More importantly, it activates an enzyme called AMPK (amp-activated protein kinase) that plays an important role in insulin signaling, systemic energy balance, and the metabolism of glucose and fats.60"
Metformin Makes Headline News - Life Extension
The Drug Virtually Everyone Should Ask their Doctor About - Life Extension
As for those taking metformin and experiencing runny bowel movements or other GI upsets i have found eating a banana or oatmeal early in the day, again near dinner solved that. Just one or the other did it for me.
Remember reading Stewie's notes that you should supplement b12 and CoQ10 to offset negative side effect of metformin depleting them. CoQ10 is best taken with fats (maybe same time you're taking exemestane)
A Practical Guide to Avoiding Drug-Induced Nutrient Depletion | Nutrition Review
Post not intended to troll or embarrass op nor diagnose health issues.