Myostatin blockers, what's new?

[chinaboy]

For a guy the size of us here you would need 300mg ACE-031 injected every 2 weeks to get results like you see in studies. Considering it sells for $170/mg who the f@$k can afford $51,000 every 2 weeks? Hahaha now if you are an oil prince in Kuwait then I suppose it's doable.

I would think Rami's crew has its own labs producing all their own gear, HGH and secret sauces with all the proper equipment and employees working on this.

No experience here, but haven't read or seen anything to suggest any of these things are worth the cost. It's also kind of a mystery what the impact on health is.

I agree. I always wonder what the longterm effect these peptides can have. Thats pretty much why I never wanted to use them. Tempting though, especially Mk-677.

 

[mikennrg]

No experience here, but haven't read or seen anything to suggest any of these things are worth the cost. It's also kind of a mystery what the impact on health is.

I think the risk of tendon rupture increases. Adding steroids that reduce collagen syntheses would increase it further.

 

[Elvia1023]

Firstly. After rereading things I probably overreacted with the above. I am sure the low carbs had something to do with it But JJ and Rambo will know what I mean because we used to get so much shit about these sort of things even though were were completely honest.

At this point you're better off stacking myostatin reducing supplements like creatine, hmb, leucine, cacao, I'm sure I'm forgetting something.

Very true. They are not going to produce amazing results but as you know everything you just listed is good for various reasons so I see no harm stacking them and hoping they may even help inhibit myostatin during cycles. I love my aminos and take creatine regularly especially around training. Cacao is another useful supplement for health and it can be energy promoting so all in all they are all good in their own right. I would take aminos and creatine regardless of myostatin as they are great for bodybuilding.

For a guy the size of us here you would need 300mg ACE-031 injected every 2 weeks to get results like you see in studies. Considering it sells for $170/mg who the f@$k can afford $51,000 every 2 weeks? Hahaha now if you are an oil prince in Kuwait then I suppose it's doable.

Other factors to consider with myo-hmp and follistatin.
Myostatin inhibitors are approximately 700+ amino acids linked together.
A peptide chain that complex is so incredibly fragile!!!
I got to use a lot of myostatin inhibitors and I'd say half were inert.
The ones that were viable were crazy but only for a very short period of time.
One vial of follistatin I took made my inclined dumbbell fly weight go from 35Lbs to 65Lbs in 2 days.
But a lot of the vials I used were dead and Nothing happened.
My IFBB PRO friend said the same thing. When it was good there was no denying the strength increase, but many times the peptide was obviously dead.
Plus, to have myo-hmp produced is so incredibly costly and takes months. The lab we had synthesize ACE-031 had to scrap several batches because it would fall apart during production.

Exactly. I can't remember the full details and would have to look back and my old posts. But that's the one thing I noticed from ACE-031. It was not placebo as the strength increase was dramatic and almost instant. I have said many times in the past if you had lots of ACE-031 it would be a fun experiment.. well if it was gtg that is. I just don't see merit in paying out for something that may be crap/inert. Plus I have seen certain brands very cheap and again I don't trust it. However I will order a few vials of the cheap one and see if it does anything. You know I love my experiments but I don't want to risk much £.

 

[Phattony]

For a guy the size of us here you would need 300mg ACE-031 injected every 2 weeks to get results like you see in studies. Considering it sells for $170/mg who the f@$k can afford $51,000 every 2 weeks? Hahaha now if you are an oil prince in Kuwait then I suppose it's doable.

Other factors to consider with myo-hmp and follistatin.
Myostatin inhibitors are approximately 700+ amino acids linked together.
A peptide chain that complex is so incredibly fragile!!!
I got to use a lot of myostatin inhibitors and I'd say half were inert.
The ones that were viable were crazy but only for a very short period of time.
One vial of follistatin I took made my inclined dumbbell fly weight go from 35Lbs to 65Lbs in 2 days.
But a lot of the vials I used were dead and Nothing happened.
My IFBB PRO friend said the same thing. When it was good there was no denying the strength increase, but many times the peptide was obviously dead.
Plus, to have myo-hmp produced is so incredibly costly and takes months. The lab we had synthesize ACE-031 had to scrap several batches because it would fall apart during production.

You would think one of these suppliers would buckle down and perfect the synthesizing process for at least one of these compounds... there has to be a fortune to be made on it if they could get the price reasonable and the product stabile and potent...

 

[Ocean cool]

What about YK-11? There isn't much experiences.

 

[Elvia1023]

What about YK-11? There isn't much experiences.

I have only used one brand and it didn't really do anything noteworthy. I was uisng aas and didn't notice a difference when adding the YK-11. I doubled the dose and it gave me a slight headache so I guess it was doing something However as I allude to earlier in this thread you simply can't judge using 1 brand of something. There are good and bad versions of everything so 1 review of 1 brand will always be limited/flawed. The one I used was by German Pharmaceuticals. Their GW was the same for me (useless) but there mdrol was decent so they weren't just selling rubbish. I have heard good things from people but I am in no rush to try it again. It's definitely doesn't have the potential some of these other Myo inhibitors possess.

 

[Floxedone]

Here is some old info I put together.
http://www.professionalmuscle.com/f...myostatin-inhibitors-eaa-50-70%-creatine.html

I do know that when I was staking all the natural supplements I did gain a bunch of weight. It was probably water weight but it's strange that would happen with these stacks.

 

[Elvia1023]

Here is some old info I put together.
http://www.professionalmuscle.com/f...myostatin-inhibitors-eaa-50-70%-creatine.html

I do know that when I was staking all the natural supplements I did gain a bunch of weight. It was probably water weight but it's strange that would happen with these stacks.

Good thread and info. I see you were using the product I am using now (cocoawell). I just use it to give me a mental boost and for the anti-oxidant properties. Even with various elements (creatine, cocoa, eaa's etc) and don't see a major difference but if it's helping then great. As I mentioned earlier in the thread most of them are great alone even forgetting about the myostatin inhibition. The water weight is not strange at all... creatine alone will do that. I have put on 10-20 pounds of water from creatine when I was natural.

 

[xman280]

So, it was 2008 when Wyeth gave up on MYO-029.

Almost 10 years later, anyone knows what's happening of importance in this field?

nothing new, every legit person who tried the chinese stuff says its not effective and the one they buy in the pharmacy in Kuwait or whatever middle eastern country caries that stuff is very potent, they just refuse to name it, I see Legit American research labs carry it at 10 times higher prices but not sure if they ll ask for some type of a chemist license or whatever to sell it ..it does make sense tho....A REAL myostatin - inhibitor will be quite a thing, jusging by scientific results , besides health -wise - don't expect anything less than a cardiomyopathy in a short period of time - a few months of continuous use...

 

[saudades]

What about the viral vector for follistatin? AVV1-fs344 I think is what it was. That stuff is still out there from what I understand.

Personal experience: I used some real acvr2b from Sino Biological (real biopharma company) a few years back. Incredibly expensive, all I could afford was 0.6mg and used half in a single dose one week, and the other half the following week. Biggest and leanest I have ever been at 217, 8-9% bf (estimating).. it was the real deal. If I had the money or a generous benefactor, I'd get 1-2 grams of that stuff.

 

[xman280]

What about the viral vector for follistatin? AVV1-fs344 I think is what it was. That stuff is still out there from what I understand.

Personal experience: I used some real acvr2b from Sino Biological (real biopharma company) a few years back. Incredibly expensive, all I could afford was 0.6mg and used half in a single dose one week, and the other half the following week. Biggest and leanest I have ever been at 217, 8-9% bf (estimating).. it was the real deal. If I had the money or a generous benefactor, I'd get 1-2 grams of that stuff.

local US based biopharm company? they didnt ask for any you can order it without any paperwork..i ve seen those companies and they charge - $400-$500 for 300mcg...

 

[saudades]

local US based biopharm company? they didnt ask for any you can order it without any paperwork..i ve seen those companies and they charge - $400-$500 for 300mcg...

No, they are based in China. I acted like a big corporation and sent them a purchase order, paid, and it arrived in a week.

 

[Sixfoottwo]

Firstly. After rereading things I probably overreacted with the above. I am sure the low carbs had something to do with it But JJ and Rambo will know what I mean because we used to get so much shit about these sort of things even though were were completely honest.




Very true. They are not going to produce amazing results but as you know everything you just listed is good for various reasons so I see no harm stacking them and hoping they may even help inhibit myostatin during cycles. I love my aminos and take creatine regularly especially around training. Cacao is another useful supplement for health and it can be energy promoting so all in all they are all good in their own right. I would take aminos and creatine regardless of myostatin as they are great for bodybuilding.



Exactly. I can't remember the full details and would have to look back and my old posts. But that's the one thing I noticed from ACE-031. It was not placebo as the strength increase was dramatic and almost instant. I have said many times in the past if you had lots of ACE-031 it would be a fun experiment.. well if it was gtg that is. I just don't see merit in paying out for something that may be crap/inert. Plus I have seen certain brands very cheap and again I don't trust it. However I will order a few vials of the cheap one and see if it does anything. You know I love my experiments but I don't want to risk much £.

What dosage are you thinking of trying? I always read how you need a couple 100 mg per month to actually notice effects so even just trying it seems like a very expensive experiment haha.

 

[Matsuo Munefusa]

Myo HMP and ACE-031 are 2 entirely different things Plus I said about the ACE-031 may not doing anything now as it's a different brand. As I mentioned in my 1st post who knows what was in those vials even if some were good and others are bad. Did I really use ACE-031 back in the day. Was it really folli etc. I haven't a clue. Even if it was ACE-031 back then how would some random brand compare... not sure of time but it must be 5 years+ later. There are 3 brand on one site I know and some are very cheap and 1 is expensive so your guess is as good as mine. I am using their lr3 and it is great but I don't trust myo products.

I have wrote the same on here about all the different myo products for years as it's simply the truth. I still say it after about 5 years and I rep no pep tide seller anymore and make no money from pep tides in anyway. Me, JJ and Rambo have put up with so many accusations over the years. I remember when we first promoted MK-677 and everyone dismissed it. Acted like we were bullshitting about an oral gh booster and look at it now. I never post like this but for years it happened with many things. We went through the myo stuff too but we never recommended those merely spoke about our experiences. I remeber a guy wanting to order $2000 worth of myo stuff which would have made me $240 and I had him not order it as I didn't trust it. That was the Superior stuff (years later) which I hadn't used at the time. Fair enough if some guy wanted to try 1 vial that was none of my business. Certain vets bullshitted about them and I remember those days but we never done that. So please don't act like I am lying on the subject and if you read both my posts you will see what I meant.

There is definitely merit in myo products but again I don't trust them and it will probably be decades before something solid comes out that is affordable.

I think your credibility was destroyed when you had multi-page discussions back and forth, back and forth, back and forth, agreeing amongst yourselves when in actuality you have no idea what was in the vials you were pumping. That's incredibly shitty man and you should feel ashamed of yourself for doing that. I'm surprised some of you were not prosecuted. It gave the illusion as if everybody on the entire forum agreed but in reality it was 2-3 people leading the discussion and drawing in unsuspecting n00bs to make sales of experimental research chemicals that you had not properly lab analyzed.

 

[ThinkTank]

I think your credibility was destroyed when you had multi-page discussions back and forth, back and forth, back and forth, agreeing amongst yourselves when in actuality you have no idea what was in the vials you were pumping. That's incredibly shitty man and you should feel ashamed of yourself for doing that. I'm surprised some of you were not prosecuted. It gave the illusion as if everybody on the entire forum agreed but in reality it was 2-3 people leading the discussion and drawing in unsuspecting n00bs to make sales of experimental research chemicals that you had not properly lab analyzed.

Shots fired! This should be good...:food-:mil

 

[Matsuo Munefusa]

^ LOL

To clarify, I don't actually remember Elvia being involved with the myostatin drug scams....which is what they were, when you have companies selling drugs that they do not even know what they are....it was a scam....but he is claiming to have been a rep for them so I am lumping him in with the bunch. If he didn't receive financial kickback for his repping then that sucks for him, but if he was receiving free drugs then that makes him as culpable. It was a shitty time on ProM....check out the discussion back then, literally 3-4 of the same people hyping up some random drugs (that cost something like 200+ USD/mg) and noobs asking questions, buying, then being puzzled why it wasn't working for them.

::tar-wars::tar-wars

 

[Elvia1023]

I think your credibility was destroyed when you had multi-page discussions back and forth, back and forth, back and forth, agreeing amongst yourselves when in actuality you have no idea what was in the vials you were pumping. That's incredibly shitty man and you should feel ashamed of yourself for doing that. I'm surprised some of you were not prosecuted. It gave the illusion as if everybody on the entire forum agreed but in reality it was 2-3 people leading the discussion and drawing in unsuspecting n00bs to make sales of experimental research chemicals that you had not properly lab analyzed.

^ LOL

To clarify, I don't actually remember Elvia being involved with the myostatin drug scams....which is what they were, when you have companies selling drugs that they do not even know what they are....it was a scam....but he is claiming to have been a rep for them so I am lumping him in with the bunch. If he didn't receive financial kickback for his repping then that sucks for him, but if he was receiving free drugs then that makes him as culpable. It was a shitty time on ProM....check out the discussion back then, literally 3-4 of the same people hyping up some random drugs (that cost something like 200+ USD/mg) and noobs asking questions, buying, then being puzzled why it wasn't working for them.

::tar-wars::tar-wars

I have got more important things to do but I don't like to be labelled like this so I will reply. I don't want to argue with anyone today. I will say you are getting mixed up. You even stated it you can't even remember me. The only thing I was guilty of the same as all the Superior reps was promotion threads. None of us recommended myo stuff and generally stayed away from it. I spoke honestly about my past experiences but that's about it. Now going back to Ergo I repped for them and they were a great company the most part. I left because of the owner and not agreeing with how he done things. I can't even remember the details but it's all fairly obvious.

Now it may interest you I run a log on folli before all the testing and I said it was ok but not worth it. The DES they sold who everyone loved I said it was crap. These were logs by their rep and I am stating I wouldn't buy them. I liked everything else though. The ACE-031 I tried was amazing and I posted details earlier. Much later on I tried Myo HMP and what did I say... completely useless. I didn't feel anything from it. So you are definitely putting me in a group of people I don't deserve to be with. It's a shame really as if you knew what I was like you would never do that.

I run my logs and post honestly and try to help when I can and take in all the amazing info written on here daily like a sponge. I don't like to write examples of look how good I am but I feel I have to prove certain things since you just attacked me. How many guys on here have pm'ed me about x product we sell and I write it's ok. I write all the time the best adrol I used were BD year ago. The best tbol was Balkan and I work for Genotec. I am as honest as the come and I think that at least deserves a bit of credit cos so many lie on here. I am probably too honest for my own good and it has caused me issues in the past.

Now if I rep for a company and one of their products out of 20 that I no power in the manufacturing process turns out bad am I a bad person. As I stated years ago you are buying countless things from Chinese sources so unless you test you simply don't know what you get. Just like the ACE-031 I used that was actually great.... was that real ace-031... I haven't a clue. Now guys who promote what they know are crap products should be banned. I only promote things I truly love and get results from. All I can do is be honest and share my experiences on here like everyone else. Although with most things I have started threads on it's pretty obvious what they are. I have not started threads on folli etc and go and check. I have threads on things like prami, melanotan 2 and lr3 etc. Most have obvious side effects and I have used them extensively. There are no fake accounts like dodgy sellers/reps that literally talk to oneanother and create discussion etc (that is fairly common).

Things like this frustrate me as I value honesty and I am simply not dodgy and many who know me behind the scenes will tell you that. Moreover loads of people did/do use pep tides so it wasn't a few people posting about it. We may have promoted but we were just passionate. Superior left on great terms and even years later I still get pm's from guys who miss them. Look at my other threads I just like to experiment... peps, aas, slin, syntherol. I have a pre workout and a coffee thread etc with reviews and pics and I don't sell any of them. I have training logs etc.

I can understand you lumping all reps in the same place as there are many bad ones but trust me I am not one of them. Many disagree with reps but I love bodybuilding and simply rep things I love. I would never promote anything I didn't use and fully believe in.

 

[johnjuanb1]

You would think one of these suppliers would buckle down and perfect the synthesizing process for at least one of these compounds... there has to be a fortune to be made on it if they could get the price reasonable and the product stabile and potent...

Why can't they sell ACE-031 in 100mg vials instead of a worthless 1mg amount?
I bet it doesn't cost much more than HGH.

 

[mikennrg]

What was the myostatin inhibitor that was supposed to only target fast twitch muscle? That one would be interesting if it's legit.

 

[xman280]

No, they are based in China. I acted like a big corporation and sent them a purchase order, paid, and it arrived in a week.

ughh, as much as i want to trust em on that particular compound, i cant, unless it s made in US, but seems currently you CAN'T buy anything manufactured in the US(made by a licensed biomed research lab) - i heard it from a few legit sources....I m trying really hard to find which one they sell in the Middle East but have no luck so far