I don't mean to sound rude or anything. But, it kind of seems like you may already know the answers to your questions, or at least suspect what the answer may be but are just looking for some confirmation. The trouble is that a lot of this is new territory for almost everyone (not the igf1-lr3, but some of the other stuff- particulars and des etc.). I do believe you'll experience less sleepiness from des. Have you tried mgf? If you try regular mgf (non pegylated) and don't get sleepy, I'm guessing you'll have a similar reaction to des. But, it's just a guess. As far as reducing dosing, I think it could help. But, you know what's coming next... I still think it's low blood sugar, just a form you aren't used to. It's hitting you harder in this way than insulin for some reason. I don't think it's as simple as just low blood sugar, but I think it's some kind of effect related to it somehow. So, and I hope that's the case, lowering your dose could help.
In the meantime, why not go off it for a few days (5-6) and let yourself get back to normal and then start a low dose from there? You won't miss much in terms of results in those few days. Either way, good luck. I hope it starts working a bit better in terms of sides.