Buy Needles And Syringes With No Prescription
M4B Store Banner
SPC-210x65
Riptropin Store banner
Generation X Bodybuilding Forum
Buy Needles And Syringes With No Prescription
Buy Needles And Syringes With No Prescription
Mysupps Store Banner
IP Gear Store Banner
Anabolic Hormones Store Banner
Ganabol Store Banner
Spend $100 and get bonus needles free at sterile syringes
Professional Muscle Store open now
LandmarkChem Email Banner
PHARMAHGH1
Bruce Labs Store banner
gd
Professional Muscle Store open now
over 5000 supplements on sale at professional muscle store
granabolic123
Blackroids-animated-optimized-number-1
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
advertise1
apollo
advertise1
kinglab
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store

Pregnenolone vs Preg/HCG combo?

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
Anybody have an opinion on the difference between backfilling just pregnenolone vs filling pregnenolone and simultaneously running HCG (daily shots or 3x weekly).

Haven’t ran HCG since two years and looking to get back on but having a lot of success right now with just test/pregnenolone/progesteron + a DHT (low dose primo).

Dunno if HCG may upset the balance? I do want to be optimized as just test/GH/a DHT has become unpleasant. Don’t care about fertility, my family has already been created.
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
On 10mg/day test e + 350mg primo/week bloodwork:
Test 470
Estradiol ultra sensitive 3 (not a typo)
SHBG 3 (yep lol)
PSA .8
Progesterone *undetectable!*
Pregnenolone (did not test this time but always been low)

Bloods were pulled at 24 hour trough but with test e everyday I’d think higher trough. I guess because ultra low SHBG I am excreting testosterone through urine rapidly.

Since blood work I’ve gone up to 20mg test e per day and added 10mg progesterone and 10mg pregnenolone transdermal (in DMSO). I feel much better. I’d hope test level is in 700s for trough and estradiol is in teens (at least) in 4 weeks. Also hope prog is in range next test.

Does anybody think HCG added in could help estradiol get in better range and also increase SHBG?
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
@Kaladryn

Anybody else welcome to throw me some advice but always have trusted Kaladryn for TRT advice. 👍
 

bad rad

Well-known member
Registered
Joined
Mar 26, 2017
Messages
863
I've been off hCG for a few years too and my libido/erection strength went with it. I use DHEA but just ordered pregnenolone and will report the changes once it comes in. I think I'll drop the DHEA and backfill the other pathways with pregnenolone.
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
I've been off hCG for a few years too and my libido/erection strength went with it. I use DHEA but just ordered pregnenolone and will report the changes once it comes in. I think I'll drop the DHEA and backfill the other pathways with pregnenolone.
It seems smart. I’ll be happy to hear what you report. The biggest change cognitively if I feel much sharper/focused on pregnenolone. Same sort of feeling I had on HCG.

I think I will wait another few weeks and test blood for all levels and if SHBG/total T/e2 hasn’t improved then I’ll add in HCG and retest after another 6 weeks.

It’s strange, just test/GH worked for years. Then all of a sudden this past year it just fell apart. Sex drive dropped, fatigue, lost focus, joints.

I’m hoping preg or preg/HCG I can regain that old good feeling.
 

buck

Well-known member
Kilo Klub Member
Registered
Joined
Apr 27, 2006
Messages
3,172
I have taken pregnenolone numerous times and noticed nothing from it, but never got any blood work. HCG has worked for me.
 

Simpllyhuge

Kilo Klub Member / Board Supporter
Kilo Klub Member
Registered
Board Supporter
Joined
Dec 29, 2011
Messages
4,528
Take preg how? Orally? Transdermaly? Supposedly it’s has different affects down stream. Also how much preg and how DHEA do you guys take?
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
Take preg how? Orally? Transdermaly? Supposedly it’s has different affects down stream. Also how much preg and how DHEA do you guys take?
Topical with DMSO

5mg AM and 5mg PM

Progesterone topical in DMSO
10mg AM on balls 10mg PM upper body
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
How is this working for you in terms of libido? EQ? Mentally ?
Libido is great but I’m always decent and right now I’m also on 140mg Test + 140mg mast so....no issues :)

Mentally I feel calm and collected. It feels like I used to feel pre-TRT. One of the drawbacks to running test has been its harder to keep my temper in check, which I hate lol

Progesterone really shouldn’t have any negative on libido, at replacement doses. If anything my dick gets harder now on progesterone. It’s way different than the progestins like nandrolone that we all know. Those are dick killers.
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
I had heard 10-14mg a day naturally produced so I’m using 20mg topical. So I’m assuming I’m absorbing 8-12mg.
 

goback2013

Well-known member
Registered
Joined
Mar 1, 2013
Messages
792
Libido is great but I’m always decent and right now I’m also on 140mg Test + 140mg mast so....no issues :)

Mentally I feel calm and collected. It feels like I used to feel pre-TRT. One of the drawbacks to running test has been its harder to keep my temper in check, which I hate lol

Progesterone really shouldn’t have any negative on libido, at replacement doses. If anything my dick gets harder now on progesterone. It’s way different than the progestins like nandrolone that we all know. Those are dick killers.
I may try the micronized progesterone thing, but with phlogel. I'm too active with a particular woman at this point for my crouch area to smell like garlic.
Although she's starting to get on my nerves. Her selfishness and controlling behavior is starting to come through. I digress.
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
I may try the micronized progesterone thing, but with phlogel. I'm too active with a particular woman at this point for my crouch area to smell like garlic.
Although she's starting to get on my nerves. Her selfishness and controlling behavior is starting to come through. I digress.
Pharm grade DMSO doesn’t have a smell, at least not very strong at all. You can know you have pharm grade if it freezes in the fridge and doesn’t bear a scent at all.

But yeah prog is cheap as fuck, I got 2,500 doses (10mg) for ~$120.
 

bad rad

Well-known member
Registered
Joined
Mar 26, 2017
Messages
863
Got my pregnenolone today. I'm taking 200mgs the first week to get my levels up and then will take 100mgs daily to assess. My last TRT consult mt doc recommended 30mgs daily but that might be because I was on DHEA too. I've dropped that for now to see what benefits I get from pregnenolone.
 

goback2013

Well-known member
Registered
Joined
Mar 1, 2013
Messages
792
Pharm grade DMSO doesn’t have a smell, at least not very strong at all. You can know you have pharm grade if it freezes in the fridge and doesn’t bear a scent at all.

But yeah prog is cheap as fuck, I got 2,500 doses (10mg) for ~$120.
Can you dm where you purchased your dmso and preg. Also your dmso solution recipe ?
 

DragonRider

New member
Newbies
Joined
Feb 26, 2003
Messages
26
Pharm grade DMSO doesn’t have a smell, at least not very strong at all. You can know you have pharm grade if it freezes in the fridge and doesn’t bear a scent at all.

But yeah prog is cheap as fuck, I got 2,500 doses (10mg) for ~$120.
Is that progesterone oral or transdermal. I like the effects I get from prog, but after a couple of months I get terrible sciatica from using it. I wonder if anyone else has? I think it has something to do with progesterone's ability to loosen ligaments and joints in the pelvic area.
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
Is that progesterone oral or transdermal. I like the effects I get from prog, but after a couple of months I get terrible sciatica from using it. I wonder if anyone else has? I think it has something to do with progesterone's ability to loosen ligaments and joints in the pelvic area.
lol...what?

The tendon/ligament loosening thing is new to me. Are you looking at data from pregnant women or something? At normal physiological male dosage do you think that’s even a thing?

I take progesterone transdermal on balls
 

bad rad

Well-known member
Registered
Joined
Mar 26, 2017
Messages
863
Well, two days in and my intestinal bloating (I have wicked IBS) is down along with sub-q water retention. I dropped inches from my naval circumference.
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,176
Yeah man definitely keep me posted! Maybe we can get more people to try it, it’s really pretty profound effect transdermal when your body is deficient in it after years of TRT.

I’ve also been reading about how HCG begins to work less and less for men as they age and direct pregnenolone/progesterone supplementation becomes more useful. This is from TRT doctors in the trenches with their patients for years.
 

bad rad

Well-known member
Registered
Joined
Mar 26, 2017
Messages
863
Yeah man definitely keep me posted! Maybe we can get more people to try it, it’s really pretty profound effect transdermal when your body is deficient in it after years of TRT.

I’ve also been reading about how HCG begins to work less and less for men as they age and direct pregnenolone/progesterone supplementation becomes more useful. This is from TRT doctors in the trenches with their patients for years.
For sure. I still respond to hcg pretty well but it's hard to find now.
 

Forum statistics

Total page views
510,080,217
Threads
125,149
Messages
2,430,164
Members
156,012
Latest member
cc8832
Top