Yes. Sermorelin is the FDA approved drug name for GHRH. The half-life of GHRH is very short (maybe less than 10 minutes). CJC-1295 is a long-lasting analog of GHRH.
Description: Sermorelin is a parenteral drug used as a growth hormone releasing hormone (GHRH). This synthetic, 29-amino acid polypeptide is the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH) and consists of 44 amino acid residues. Sermorelin appears to be equivalent to endogenous GHRH in its ability to stimulate growth hormone secretion in humans. Sermorelin is used to treat growth hormone deficiency (e.g., Geref®, FDA-approved in October 1997) and also as a diagnostic agent to evaluate the ability of the somatotroph of the pituitary gland to secrete growth hormone (e.g., Geref® Diagnostic, FDA-approved in 1991).
Sermorelin acetate for subcutaneous injection is a sterile, nonpyrogenic, lyophilized powder (powder contains 5 mg mannitol, monobasic and dibasic sodium phosphate; and may contain up to 1% Human albumin). Store unopened vials under refrigeration (2—8°C). Rx only. Supplied as 1 vial containing 0.5-mg sermorelin acetate packaged with a vial of 2-ml Sodium Chloride Injection, USP. NDC 44087-4005-1. Also supplied as 1 vial containing 1-mg sermorelin acetate with a vial of 2-ml Sodium Chloride Injection, USP. NDC 44087-4010-1.
Dosage:
Subcutaneous Administration (Geref®)
•For subcutaneous use only.
•Dosages are usually administered once daily before bedtime.
•Use aseptic technique.
•After determining the appropriate patient dose, reconstitute each vial with 0.5—1 ml of Sodium Chloride Injection, USP. Inject the diluent into the vial by aiming the liquid against the glass vial wall. Swirl the vial gently until contents are dissolved completely.
•Use immediately after reconstitution. Discard unused material. Do not administer if particles are visible in the reconstituted solution or if the reconstituted solution is cloudy.
•Use administration syringes of small enough volume that the prescribed dose can be accurately drawn from the vial.
•Instruct patients/parents on the proper use and disposal of syringes and needles.