Yes, especially with the weaker ghrps like ghrp6 and ipam. In the studies, gh and igf rose dose dependant. Remember the study about MK677 (similar structure to ghrp6), 50mg only had a slight increase in gh serums over 10mg however 50mg had a significant rise in igf serums over 10mg.
After administration of 10mg MK-677, igf-1 concentrations increased 52% and 24hr GH concentrations increased 79% from baseline.
After administration of 50mg MK-677, igf-1 concentrations increased 79% and 24hr GH concentrations increased 82% from baseline.
So my belief is the higher doses cause much larger increases in igf serums. I notice this when I can't walk half a mile without getting an insane pump in my legs. I carry my son and my arms get pumped, etc.