Well I was looking uup some pharmacology and I'm glad I did. Usually 5 times the half life means that 97% of the drug is gone, so you'd think undetectable, right?
Well: Unless I find out the detection levels, here is hte safest info:
From my text: Clinical Pharmacology:
Clomid (Clomiphene)
"The half-life of clomiphene is reported to be 5 days, but studies with radiolabeled doses have demonstrated that the drug may be found ... for up to 6 weeks."
...
Tamoxifen is more complex. Tamoxifen has metabolites before it is gotten rid of. Therefore, I will take the longest half life for an example and use my 5 half life example. Lets asssume that detectability is cut-off at 3% of usual dose.
Tamoxifen has a 5 day half-life. However, this doesn't mean it's out of the body. It merely means it is transformed into another compound (which is usually inactive). In this case, the major metabolite (compound) is N-desmethyltamoxifen. This metabolite has a half-life of 14 days. So, in summary it takes about 5 days to change half of the tamoxifen into its metabolite and 14 days to get rid of half of the metabolite. You would think you should just add the taxofen half-life and metabolite half life together to get a new half life. However, these process are occurring at the same time (simultaneously). So, with a little fudging you can assume that these products will be gone in about 3.3 half-lives or the time it takes to get rid of 90% of the drug and 5 days x 3.3 + 14 days x 3.3 = about 60 days.
So, I would guess about 60 days for tamoxifen
and
as the article states above., about 6 weeks for clomid.
Again, tamoxifen and clomid may be banned. But they have banned several substances in the past without even having a test for them. Now, this would be an expensive assay to run on everyone or even randomly. So, someone needs to get on the inside and find out if they're really sending this out.
.gif "IP Gear")
