Boldon, Primo lowering E2

[IRON1977]

Hi guys,

It have been proved that Primo and Boldenon lowering E2 when you take test.

My question , is it the same with Deca ? deca aromatise less than test but mayby its not the same mechanisme , i don t know ?

I asl because the oestrogene you produce with ment is not the same you produce with Test , this is why i ask myself mayby bold don t have the same action , if someone made a bloodwork when he takes test deca , bold or primo

Best regards

 

[slesh]

Hi guys,

It have been proved that Primo and Boldenon lowering E2 when you take test.

My question , is it the same with Deca ? deca aromatise less than test but mayby its not the same mechanisme , i don t know ?

I asl because the oestrogene you produce with ment is not the same you produce with Test , this is why i ask myself mayby bold don t have the same action , if someone made a bloodwork when he takes test deca , bold or primo

Best regards

I don’t know that this has been “proven”. I believe it’s anecdotal broscience and does work for some of us.

 

[FrenchBench22]

Boldenone has a potential metabolite (1,4,6-Androstatriene-3,17-dione) that is a suicide aromatase inhibitor.

https://pubmed.ncbi.nlm.nih.gov/19089863/

Primobolan and Proviron produce a metabolite (#12) that is a suicide aromatase inhibitor, atamestane, 1-methyl-3-oxoandrosta-1,4-dien-3,17-dione.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076145/

However the rate at which an individual produces these metabolites will vary from person to person, which is why one person can run test and primo at 1:1 with no issue, and the next guy might have lowered estrogen.

 

[TheOtherOne55]

Hi guys,

It have been proved that Primo and Boldenon lowering E2 when you take test.

My question , is it the same with Deca ? deca aromatise less than test but mayby its not the same mechanisme , i don t know ?

I asl because the oestrogene you produce with ment is not the same you produce with Test , this is why i ask myself mayby bold don t have the same action , if someone made a bloodwork when he takes test deca , bold or primo

Best regards

Proven but only having to do with certain metabolites that affect certain individuals. So verrry dependent on the person.

And no deca is nothing like that.

 

[VaginaBoob89]

Boldenone has a potential metabolite (1,4,6-Androstatriene-3,17-dione) that is a suicide aromatase inhibitor.

https://pubmed.ncbi.nlm.nih.gov/19089863/

Primobolan and Proviron produce a metabolite (#12) that is a suicide aromatase inhibitor, atamestane, 1-methyl-3-oxoandrosta-1,4-dien-3,17-dione.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076145/

However the rate at which an individual produces these metabolites will vary from person to person, which is why one person can run test and primo at 1:1 with no issue, and the next guy might have lowered estrogen.

I'm dumb. If I use boldenone with ment, could this metabolite block conversion of ment as well as testosterone?

 

[IRON1977]

Boldenone has a potential metabolite (1,4,6-Androstatriene-3,17-dione) that is a suicide aromatase inhibitor.

https://pubmed.ncbi.nlm.nih.gov/19089863/

Primobolan and Proviron produce a metabolite (#12) that is a suicide aromatase inhibitor, atamestane, 1-methyl-3-oxoandrosta-1,4-dien-3,17-dione.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076145/

However the rate at which an individual produces these metabolites will vary from person to person, which is why one person can run test and primo at 1:1 with no issue, and the next guy might have lowered estrogen.

yes exactly what i heard and see in people thats experienced it

 

[IRON1977]

I'm dumb. If I use boldenone with ment, could this metabolite block conversion of ment as well as testosterone?

The oestrogene from ment is a hybrid , you can not mesure it in bloodwork but is oestroegene, i ask me the same question

 

[IRON1977]

Proven but only having to do with certain metabolites that affect certain individuals. So verrry dependent on the person.

And no deca is nothing like that.

is the oestrogene produced by deca the same as test ? thats the question

 

[nothuman]

I'm dumb. If I use boldenone with ment, could this metabolite block conversion of ment as well as testosterone?

The oestrogene from ment is a hybrid , you can not mesure it in bloodwork but is oestroegene, i ask me the same question

I think it’s a really smart question and I’d also like the know the answer

 

[Doitagain]

I think it’s a really smart question and I’d also like the know the answer

I doubt anyone can answer this. The theory is that Boldenone is a much better substrate for Aromatase than Test and this yields a different, weaker metabolite than E2 (allegedly Estrone or something that cross-reacts with E1 at least) and it makes sense. Same scenario with MENT? Who knows.

 

[Mufasa123]

If the estrogen like metabolite can be tested for, then one could take an Ai and see if it is successful in blocking or reducing it.

1) Take Ment alone and see what shows up on E1/E2 or estradiol panel (use a sensative)
2) Add an Ai and repeat test noting any differences.

Would probably help a lot of people to know. Seems logical.

 

[Doitagain]

If the estrogen like metabolite can be tested for, then one could take an Ai and see if it is successful in blocking or reducing it.

1) Take Ment alone and see what shows up on E1/E2 or estradiol panel (use a sensative)
2) Add an Ai and repeat test noting any differences.

Would probably help a lot of people to know. Seems logical.

I'm pretty sure that 7α-Methylestradiol does not shows up as E2 or E1 in a sensitive assay...

 

[Mufasa123]

I'm pretty sure that 7α-Methylestradiol does not shows up as E2 or E1 in a sensitive assay...

I figured. I think I recall hearing that before. If aromatase enzyme is converting it, theoretically an Ai should work, albeit no easy test.

Sadly lots of "theoretically sound" shit isn't necessarily so. Example gyno from a dht/Anadrol or E2 suppression from primo/equipoise and who knows what else. Lol

 

[ironmaster73]

I have seen it on blood work with the guys I help. One of the guys I help is very sensitive to estrogen. We found that on trt 180mg/wk he would have a blood test and e2 was 150pg/ml. So we tried mirco dosing 0.25ml EOD and tested e2 5 weeks later and the results for his trt came in as follows. TT 800ng/dl E2 45pg/ml. Those having issues with e2 for trt micro dosing works to help keep e2 in healthy ranges. Now when this same guy wanted to run a cycle we I had him do 250mg/wk of test e on monday and 300mg/wk of primobolan on thursdays no ai over 12 weeks. We tested his e2 at week 8 and his e2 was 17pg/ml. Goes to show primo can lower e2 very well. The estrogen on this cycle was on the low side so next time I would have him run his test a bit higher than his prim dose. I myself only aromatize moderatly and find I can d my trt 100mg spaced out over tw injection per week for a total of 200mg/wk. I have never ran primo but planning on trying ti soon and hping to keep the test/primo at 1:1 and not have to use an ai.

 

[Swifto]

Primo or EQ do not lower estrogen for me at all.

Actually, my estrogen was higher on Test + EQ than Test alone.

 

[luki7788]

Primo or EQ do not lower estrogen for me at all.

Actually, my estrogen was higher on Test + EQ than Test alone.

if you use a regular e2 test it will be like that because it will detect all estrogens as e2 and the difference is huge in my case on 1750 test and 1000mg EQ the regular test showed e2 at a crazy level of 300+ where the top test done the same day showed 15 lol

 

[curcumin]

Primo or EQ do not lower estrogen for me at all.

Actually, my estrogen was higher on Test + EQ than Test alone.

no idea about EQ because I already have enough hematocrit problems and it skyrockets HCT for me. But with Primo you need to use the "ultrasensitive assay" to get an accurate reading otherwise they pick up estrone or other types of estrogen, you only want the e2 number - pain in my ass because it takes the lab like 2 weeks to get the results back to me. But I have proven (to myself) that primo lowers estradiol in my body. So much to the point that unless I am on a cycle dose of test (which I will never use again) then I can only use MAXIMUM 50mg primo per week if I want estradiol over 40 (I like it 40-50ish on TRT). 200mg test/35mg primo is perfect for me. I was undetectable E2 levels on 1:1 primo/test dosage at TRT levels. Felt like complete shit.

Obviously there's not much of an anabolic muscle building effect at this dosage of the primo. Its simply in there as an AI and to replace a little DHT to a marginal extent.

 

[Doitagain]

if you use a regular e2 test it will be like that because it will detect all estrogens as e2 and the difference is huge in my case on 1750 test and 1000mg EQ the regular test showed e2 at a crazy level of 300+ where the top test done the same day showed 15 lol

Told you this FOREVER when you were using Letro as that worthless test showed falsely elevated E2
Glad you finally found a lab using the ultra sensitive test!

 

[nothuman]

no idea about EQ because I already have enough hematocrit problems and it skyrockets HCT for me. But with Primo you need to use the "ultrasensitive assay" to get an accurate reading otherwise they pick up estrone or other types of estrogen, you only want the e2 number - pain in my ass because it takes the lab like 2 weeks to get the results back to me. But I have proven (to myself) that primo lowers estradiol in my body. So much to the point that unless I am on a cycle dose of test (which I will never use again) then I can only use MAXIMUM 50mg primo per week if I want estradiol over 40 (I like it 40-50ish on TRT). 200mg test/35mg primo is perfect for me. I was undetectable E2 levels on 1:1 primo/test dosage at TRT levels. Felt like complete shit.

Obviously there's not much of an anabolic muscle building effect at this dosage of the primo. Its simply in there as an AI and to replace a little DHT to a marginal extent.

I also get a strong estrogen lowering effect on primo, to the point its only use for me is in low doses if I want an AI effect. I can’t really use high enough dosages for anabolism unless I run higher test than I am used to, or else my estrogen will be too low.

 

[Mufasa123]

if you use a regular e2 test it will be like that because it will detect all estrogens as e2 and the difference is huge in my case on 1750 test and 1000mg EQ the regular test showed e2 at a crazy level of 300+ where the top test done the same day showed 15 lol

Holy shit!