Gear in your system

[engbulldog]

How long does test stay in your system after your last shot? Someone told me if you run a 12wk cycle it takes 12wks for it to get out of your system kinda like a wk for wk thing? now does your receptors clean out also? The reason i ask is I've been off for 1 mth and it looks like I'll be off for 3 more at least. Is there any thing that cleans your receptors out so when you get back on, your body uses it to its fullest? Or is time the only thing that works?

thanks engbulldog

 

[StudHammer]

Depends on the ester of the test you used. What was you on?

 

[Dad]

Eng,

Clearance time depends on the half-life of the drug. For example, test cyp has a half-life of 8 days. So, clinically, we use 5 half-lives to either build up to a staedy state, or clear once yuo stop adminstration (mathematically it's more like 7 half-lives).

So, again using test cyp as an example, it will take about 40 days (perhaps as long as 56 days) to clear yuor system after yuor last shot. It doesn't matter what the dosing was - because of the way the drug clears (first order kinetics), the time will be the same because as each 8 day half-life goes by, the dose is calculated to be reduced by half.

So bottom line: Get the half-life for the drug(s) you're using, multiply by 5, and this is about the time it will take to clear.

As to receptors, these are simply folded up proteins, and have a life span just like any other cell or cell component. They are constantly being replaced and renewed, so the idea of "clearing receptors" has limited, if any, usefulness, I suspect. There is probably some arcane research out there that addresses this, but I've not read any, nor have I really looked. I know this has been talked about a lot, but would like to hear what the basis is for this idea.

 

[engbulldog]

Thanks for the info that clears things up for me

 

[Noir]

Eng,

Clearance time depends on the half-life of the drug. For example, test cyp has a half-life of 8 days. So, clinically, we use 5 half-lives to either build up to a staedy state, or clear once yuo stop adminstration (mathematically it's more like 7 half-lives).

So, again using test cyp as an example, it will take about 40 days (perhaps as long as 56 days) to clear yuor system after yuor last shot. It doesn't matter what the dosing was - because of the way the drug clears (first order kinetics), the time will be the same because as each 8 day half-life goes by, the dose is calculated to be reduced by half.

So bottom line: Get the half-life for the drug(s) you're using, multiply by 5, and this is about the time it will take to clear.

As to receptors, these are simply folded up proteins, and have a life span just like any other cell or cell component. They are constantly being replaced and renewed, so the idea of "clearing receptors" has limited, if any, usefulness, I suspect. There is probably some arcane research out there that addresses this, but I've not read any, nor have I really looked. I know this has been talked about a lot, but would like to hear what the basis is for this idea.

great answer thx for the info