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GH Scheme: Prevent suppression of GH secretion and sensitivity

TrenE

New member
Newbies
Joined
Sep 2, 2020
Messages
2
Hello,

Taking GH ED vs EOD in terms of preventing suppression of own GH secretion and sensitivity to it was discussed often here based on the below study. The study shows that EOD group immediately after treatment returned to the values (growth rate) that were present before the study began. In the ED group a recovery of these values takes about 2 years.

EOD seems beneficial over ED to prevent this suppression. But I assume EOD is disadvantageous regarding fat loss (but not for bulking).

What is the current state of knowledge to use GH effectively with focus of fat loss/lean bulk and prevent suppression of own GH production and sensitivity after withdrawal?

What do you think about using GH 5on2off profiting more days from fat loss effects but also prevent suppressing effects on own GH secretion? I could not find a study which researchs suppressing effects on 5on2 compared to EOD or ED.

Thank you.

[...]Everyday injections seems to drastically lower your body's sensitivity to it's own GH secretion. The study included children with idiopathic short stature, but can be ever casting on us, normal non-deficient hGH individuals who may use hGH periodically for bodybuilding, sports and health purposes.
[...]
You can read the full article with all the graphs and details here:
Prevention of Growth Deceleration after Withdrawal of Growth Hormone Therapy in Idiopathic Short Stature
 

b_cornelius

Well-known member
Kilo Klub Member
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Joined
Jul 25, 2012
Messages
1,367
Ummm, all those GH secretagogues will do the trick. And/Or you could focus on lowering the negative feedback mechanisms, somatostatin, etc. Once you get the feedback under control, a solid dose of GHRH with a GHRLN analogue can kick start your pituitary. Similarly, one shot of GnRH kick-starts gonadotropins after steroid use. Some times, it has been found that it it necessary to administer the releasing hormones monthly as a legitimate therapy.
 

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