Interesting. I should switch to sub-q
I don't know if were catching this here, but according to that chart, the I.M. dosage was a mere 10% of the SQ dose, yet the I.M spike lasted about the same duration as the SQ. Based on that alone, I.M. would be the better choice between those two, but not necessarily between the three.
By the way, I was PM'ed by someone who raised a point I too saw, but shrugged off as a misprint. The way the chart reads, 0.1 SQ and 0.10 I.M are protrayed as if they are different dosages, yet .1 and .10 are actually the same dose! However as the chart seems to suggest the dosages varied and I'm assumming (like other studies mostly do) SQ was the greater dose, I.M. second and I.V. the least.
It would certainly be nice to know whether or not the SQ and IM varied or not. Might I add, if there's no variation in dosage between these two, then SQ certainly appears to be the preferred choice.
Now depending on the misprint, I.V. was either only dosing 10% of the others or as little as only 2%.
Either shows an incredible benefit for I.V. dosing. That is, I.V. spiked approx 6x greater at reduced dosage -- meaning if the I.V. dosage was raised, in theory, the I.V. spike/peak could have exceeded 60x to 600x greater, again, dependent on misprint! I know that seems far fetched, but it does seem appropriate. To explain -
Again, pay attention to the other study I gave links for which compared SQ (SC), I.V. and I.N. injections. It said,
"On the other two occasions the patients received an sc injection (0.10 IU/kg) and an iv injection (0.015 IU/kg) of GH, respectively."
Did you catch the difference in dosage? I.V. was only 1/8th of the SQ dose! However check out the spike/peaks!
"Intravenous administration produced a short-lived serum GH peak value of 128.12 ± 6.71 μg/l. Peak levels were 13.98±1.63 μg/l after sc injection "
I find that AMAZING and certainly useful. The I.V. just didn't double. i.e. increase 100%. Hell no! It increased approx 1000% above the SC dose.
Yeah, yeah, I know it's "a short-lived" spike/peak and according to the chart above and at the MINIMAL dosages we've seen so far, it seems we can expect (at minimum) a 2 hour window. However I keep thinking, what if we upped the dosages? How high the peak would really be? Would it stay true to the math? But more importantly, how long before it dropped back to base line? Again, we're dealing with minimal dosing.
Lastly, I know many in this forum dose as much as every 3 hours. If you were to implement I.V. into you routine, maybe splitting up your doses, i.e. 1/3rd IV and 2/3rds part SQ, you could experience the benefits of both worlds. You'd also confuse the body a tad as well via
mixing up the dosing.
In the end, your dosing would be higher, your peaks would last longer, you'd mix up your protocol and use LESS because only minimal amounts are needed when dosing I.V.