did some one tell you l-glutamine was garbage??????? its one the most important amino acids in the body, your body will depleat your glutamine levels during a Intense workout! glutamine is good for skeletal muscle growth, joints, ligaments, and your immune system!!!!!! it is a must in my supplement regime... i like to use it pre workout n pwo and b4 bed... taking it with food might not allow total abbsorbtion like mentioned above..... u can get around that by taking it on empty stomach b4 you eat...i will say taking it b4 bed is very important it has been said to increase your bodies own natural HGH levels threw out the night which is a GOOD thing.....