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long acting gh trials

asteelz

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https://academic.oup.com/jcem/article/2965085/Long-Acting-CTP-Modified-hGH-MOD-4023-Results-of-a

This got published on the 31st, got to love the early release and free articles.

CTP-modified hGH (MOD-4023) was administered weekly at a dose of either 0.25, 0.48, or 0.66 mg/kg/week, and compared to daily hGH at a dose of 0.24 mg/kg/week.

MOD-4023 showed an estimated half-life approximately 5- to 10-fold longer when compared to daily r-hGH. IGF-I and IGFBP-3 showed dose-dependent increase during MOD-4023 treatment. IGF-I SDS for MOD-4023 did not exceed +2. All MOD-4023 cohorts demonstrated adequate catch-up growth. The 0.66 mg/kg/week dose demonstrated efficacy closest to daily r-hGH. No serious adverse events were observed during MOD-4023 treatment, and its tolerability was consistent with known properties of r-hGH.

Seems promising for patients,practitioners..with clear implications in sports and bodybuilding.
 

asteelz

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As far as I know it's not available commercially
 

goal245

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The .66mg/kg/wk would translate to 32iu per day for a 250lbs person. It's funny how everyone on the forums freaks out if anyone is taking 10iu per day lol
 

asteelz

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16iu but still a large dose
 

gungalunga

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I wonder how long it will take before this is available. Less injects would be nice.
 
Last edited:

asteelz

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Figure phase 2 trials , could be anywhere from 3-5 years
 

asteelz

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Haha that's all you brother, imagine dosing too much and dealing with sides for a wrk instead of a few days ? I'll let my more adventurous bros try it out first and establish safe dosing parameters for bodybuilding purposes :)
 

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