Research points to sildenafil (Viagra) as a potential treatment for Alzheimer’s disease

[Fleezy]

Cleveland Clinic-Led Research Supports Repurposing Sildenafil (Viagra) For Alzheimer’s Treatment

New Cleveland Clinic-led research points to sildenafil (Viagra) as a potential treatment for Alzheimer’s disease. The study provides evidence from computational models, insurance claims data and observations from brain cells in Alzheimer’s patients. Sildenafil is the main component of drugs...

newsroom.clevelandclinic.org

"In brain cells from Alzheimer’s patients, researchers also showed that sildenafil lowers levels of neurotoxic tau proteins, which are known to be associated with Alzheimer’s disease when they build up. They also found that neurons treated with sildenafil expressed genes related to cell growth, improved brain function, reduced inflammation and other processes known to protect against the neural degeneration associated with Alzheimer’s disease."



boner time

 

[steve0691]

Pretty interesting how the researchers identified it as a potential treatment. Too bad i get such bad nasal congestion from it to the point ive given up

 

[nothuman]

It’s only the latest in a growing list of evidence showing Viagra probably extends human lifespan. hopefully cialis has a similar effect

Longevity Briefs: 14 Drugs That Might Extend Human Lifespan Are Already In Use - Gowing Life

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Note that SGLT2 drugs (Jardiance being the most prescribed) came out looking very strong here too, which all the smart people take.

 

[Isovet]

Pretty interesting how the researchers identified it as a potential treatment. Too bad i get such bad nasal congestion from it to the point ive given up

I get stuffy head too on viagra.. but id take a stuffy nose to make sure i didnt run out in the street naked as a 90 year old

 

[Virtuous]

there’s a joke somewhere in here about making everyone’s head better.

But seriously, that’s neat. I usually take a bit of Cialis, or a Cialis/viagra blend most days.

 

[alfresco]

there’s a joke somewhere in here about making everyone’s head better.

But seriously, that’s neat. I usually take a bit of Cialis, or a Cialis/viagra blend most days.

My Uro go with 50mg. . . . don’t know about my wife.

20mg does nothing for me, in the gym or bed (not that I need it even at 69 1/2.
Always scared me to go higher (priapism).

Might talk to him about this. Or my GP which is probably a better option.

Now if only I can remember to ask him.

 

[nothuman]

My Uro go with 50mg. . . . don’t know about my wife.

20mg does nothing for me, in the gym or bed (not that I need it even at 69 1/2.
Always scared me to go higher (priapism).

Might talk to him about this. Or my GP which is probably a better option.

Now if only I can remember to ask him.

But it could be reducing your risk for alzheimers...

 

[alfresco]

But it could be reducing your risk for alzheimers...

Thanks.

I know that.

I think they said 50mg daily, no?

I would take a higher (.5) dose daily for what you and the report said. I will be interesting to see what doc says. My gut tells no dice.

 

[EnhancedFatGrappler]

My Uro go with 50mg. . . . don’t know about my wife.

20mg does nothing for me, in the gym or bed (not that I need it even at 69 1/2.
Always scared me to go higher (priapism).

Might talk to him about this. Or my GP which is probably a better option.

Now if only I can remember to ask him.

I only had one case of priapism, and that was from Caverject (took too much). I have taken a lot of Cialis and even stacked it with Viagra, there was never any issue with that. My nose was sealed shut though, and my heartburn was so bad, I had to sleep almost upright lol.

 

[Virtuous]

My Uro go with 50mg. . . . don’t know about my wife.

20mg does nothing for me, in the gym or bed (not that I need it even at 69 1/2.
Always scared me to go higher (priapism).

Might talk to him about this. Or my GP which is probably a better option.

Now if only I can remember to ask him.

I had a priapism last fall.

It was not fun having to chat with a nurse about how to fix it, especially since my wife came

 

[nothuman]

Thanks.

I know that.

I think they said 50mg daily, no?

I would take a higher (.5) dose daily for what you and the report said. I will be interesting to see what doc says. My gut tells no dice.

Well we don't know. It could be that we could still get benefits with less.

 

[danieltx]

Generation Z might finally be the ones that get a cure or a very effective treatment for Alzheimer's. We're in a golden age of research on it right now with stuff like this, its connection to the gut biome, etc.

 

[buck]

As diminishing blood flow as one ages which is normal causes issues. I can see where anything that allows blood to flow better can have a positive effect on most all parts of the body.

 

[Muay Thai]

O/t there's a vice doc on a dude who was paralyzed partially and accidently took a calis and it granted him some motor skills. It's being studied now off label

 

[Virtuous]

O/t there's a vice doc on a dude who was paralyzed partially and accidently took a calis and it granted him some motor skills. It's being studied now off label

Damn now I want to see an epidemiology study comparing dudes who took boner pills vs not, contrasting all health outcomes

 

[RandomMachine]

Now I can tell that girl at the pharmacy I'm taking Viagra for lifespan extension not penis extension.

Maybe she'll stop giving me strange looks when I pick them up.

 

[Fa Seeshus]

Now I can tell that girl at the pharmacy I'm taking Viagra for lifespan extension not penis extension.

Maybe she'll stop giving me strange looks when I pick them up.

One lady at vitamin shoppe never actually used the supplements and thought the Xtend amino acids I was always buying were for penile enhancement.

 

[danieltx]

One lady at vitamin shoppe never actually used the supplements and thought the Xtend amino acids I was always buying were for penile enhancement.

An honest mistake considering all the advertising ExtenZe was doing 20 years ago.

 

[nothuman]

An honest mistake considering all the advertising ExtenZe was doing 20 years ago.

That blonde chick on the ads was so hot

 

[jcc80]

Cleveland Clinic-Led Research Supports Repurposing Sildenafil (Viagra) For Alzheimer’s Treatment

New Cleveland Clinic-led research points to sildenafil (Viagra) as a potential treatment for Alzheimer’s disease. The study provides evidence from computational models, insurance claims data and observations from brain cells in Alzheimer’s patients. Sildenafil is the main component of drugs...

newsroom.clevelandclinic.org

"In brain cells from Alzheimer’s patients, researchers also showed that sildenafil lowers levels of neurotoxic tau proteins, which are known to be associated with Alzheimer’s disease when they build up. They also found that neurons treated with sildenafil expressed genes related to cell growth, improved brain function, reduced inflammation and other processes known to protect against the neural degeneration associated with Alzheimer’s disease."



boner time