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Reversing and Preventing Left Ventricular Hypertrophy

trenaffleck

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Most bodybuilders and serious athletes will have some degree of LVH. As heart disease runs in my family I have looked in to reversing/preventing LVH. The good news is there are a number of things that help, I wanted to share the top five as far as I can tell:


1) L-carnitine

https://www.ncbi.nlm.nih.gov/pubmed/18503218

Supplementation with L-carnitine induced regression of LVH in patients on hemodialysis, even for those with normal systolic function.

2) CoQ

https://www.ncbi.nlm.nih.gov/pubmed/9266516

All patients noted improvement in symptoms of fatigue and dyspnea with no side effects noted. The mean interventricular septal thickness improved significantly

3) Taurine

https://www.researchgate.net/public...hypertrophy_in_renovascular_hypertensive_rats

Taurine which effectively suppress myocardial cell hypertrophy and collagenous fiber productive reaction by decreasing myocardial local RAAS and c-fos mRNA expression can produce good preventive effect on left ventricle hypertrophy caused by renal hypertension.

4) Testosterone

https://www.ncbi.nlm.nih.gov/pubmed/14713281

The results of the present study are consistent with the hypothesis that lower levels of testosterone in men are associated with higher blood pressure, left ventricular mass, and left ventricular hypertrophy.

5) Vitamin D

https://www.ncbi.nlm.nih.gov/pubmed/15882312

Recent studies using vitamin D receptor deficient mice as a model demonstrate a crucial role of vitamin D in regulation of the renin-angiotensin system. Additionally, there is emerging evidence linking treatment with vitamin D to improved survival on hemodialysis and improvement in cardiac function. The emergence of this data is focusing attention on the previously underappreciated nonmineral homeostatic effects of vitamin D that very likely play an important role in the pathogenesis of cardiac disease in ESRD.

https://www.ncbi.nlm.nih.gov/pubmed/21937207

In the absence of major cardiovascular risk factors, 25(OH)D deficiency is a frequent finding in EH patients and is independently associated with LVH.


Honorable mention) Possibly fish oil:

https://www.ncbi.nlm.nih.gov/pubmed/18360184

In summary, any patient with documented coronary heart disease and those with risk factors for sudden cardiac death, such as left ventricular dysfunction, left ventricular hypertrophy, prior myocardial infarction, or high-grade ventricular dysrhythmias, should consider fish oil supplementation.
 

Bio

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This has all been discussed many times before, especially in some of Dante's threads.
 

liv2pb

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My apologies then, hopefully this is new and useful for some.

We can never use enough of these threads. New people are always coming on board and have no clue about previous threads. It's also a good refresher to those of us who already know these things.
 

STEVO 47

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We can never use enough of these threads. New people are always coming on board and have no clue about previous threads. It's also a good refresher to those of us who already know these things.

Absolutely. Couldn't find Dante's posts Bio but want to give an input on the good news I received today. Last year was diagnosed with enlarged weak heart and thickened LVH from undetected high blood pressure. After a year treating with medication fish oil along with circumin and aspirin. Had my echo today. Cardiologist said everything looks great. States that caught in time all these symptoms can be reversed. Like a rubber band around a rolled up news paper. If left on long enough the band will stay stretched permanently but taken off in time will reform back to it's original shape.
 

trenaffleck

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Congratulations Stevo, great to hear some of these things can be reversed. Another reason to get to the doctor and not bury one's head in the sand, there's things that can be done and time is of the essence.
 

STEVO 47

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Congratulations Stevo, great to hear some of these things can be reversed. Another reason to get to the doctor and not bury one's head in the sand, there's things that can be done and time is of the essence.


Thanks ! For one whole year was worried that I permanently screwed my self and life would never be the same. Hearing this today was one of the happiest days of my life. Funny how you just bought this back up right after my test.
 

maldorf

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Absolutely. Couldn't find Dante's posts Bio but want to give an input on the good news I received today. Last year was diagnosed with enlarged weak heart and thickened LVH from undetected high blood pressure. After a year treating with medication fish oil along with circumin and aspirin. Had my echo today. Cardiologist said everything looks great. States that caught in time all these symptoms can be reversed. Like a rubber band around a rolled up news paper. If left on long enough the band will stay stretched permanently but taken off in time will reform back to it's original shape.

Good news! I had cardiomyopathy and my heart was stiff and ejection fraction was only about 35%. I got off all the shit and within a year mine was back up to a normal 55%-60% or so. In my case my BP wasn't high at the time but had been in the past when I was running gear. Some changes are due to more than just high BP though. Getting off the sauce cured my problem. I went back on though the next year, Wrong decision on my part.

Are you still on now?
 

liv2pb

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Thanks ! For one whole year was worried that I permanently screwed my self and life would never be the same. Hearing this today was one of the happiest days of my life. Funny how you just bought this back up right after my test.

I assumed that once your heart/valves are enlarged them your screwed as well. Glad to here that your doing fine and that this can actually be reversed!
 

STEVO 47

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Good news! I had cardiomyopathy and my heart was stiff and ejection fraction was only about 35%. I got off all the shit and within a year mine was back up to a normal 55%-60% or so. In my case my BP wasn't high at the time but had been in the past when I was running gear. Some changes are due to more than just high BP though. Getting off the sauce cured my problem. I went back on though the next year, Wrong decision on my part.

Are you still on now?

Was doing around 1500 test weekly before then dropped it to 500 for the past year and still at that. May go down more if blood pressure goes up. But I also smoked and cut back on that too.
 
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STEVO 47

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I assumed that once your heart/valves are enlarged them your screwed as well. Glad to here that your doing fine and that this can actually be reversed!

Yep. As long as you get it in time. Heard so many different scenarios didn't know what to believe till now....
 

STEVO 47

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Good news! I had cardiomyopathy and my heart was stiff and ejection fraction was only about 35%. I got off all the shit and within a year mine was back up to a normal 55%-60% or so. In my case my BP wasn't high at the time but had been in the past when I was running gear. Some changes are due to more than just high BP though. Getting off the sauce cured my problem. I went back on though the next year, Wrong decision on my part.

Are you still on now?

maldorf, wanted to add that my ef was also 35 to 40 % but the doctor said more like 35.
 

Maelstrom

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Telmisartan and TB500 both show promise in reversing LVH. This is just another of the many reasons why most bodybuilders should take telmisarten.
 

maldorf

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maldorf, wanted to add that my ef was also 35 to 40 % but the doctor said more like 35.

So it recovered like mine did up to mid 50s or higher and you were still on 500 mg/wk test the whole time? Just wondering. With my case I was clean the whole year and it went back to normal. When I went back on test, tren, etc I ended up with my heart attack about 4 years later.
 

IronLion2

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No ones going to mention the NEED for cardio to help mitigate heart disease? A mixture of LISS and HIIT most of the year is a healthy choice, not just for body composition, but internal health.
 

STEVO 47

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So it recovered like mine did up to mid 50s or higher and you were still on 500 mg/wk test the whole time? Just wondering. With my case I was clean the whole year and it went back to normal. When I went back on test, tren, etc I ended up with my heart attack about 4 years later.


Yes, when diagnosed with cardiomyopathy dropped to 500mg's and kept an eye on blood pressure. As long as it was lowering at that dose stayed there.
Never did tren or anything else but test and a little d-bol. Figured if I couldn't grow on that screw it.
 

nothuman

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Most bodybuilders and serious athletes will have some degree of LVH. As heart disease runs in my family I have looked in to reversing/preventing LVH. The good news is there are a number of things that help, I wanted to share the top five as far as I can tell:


1) L-carnitine

https://www.ncbi.nlm.nih.gov/pubmed/18503218

Supplementation with L-carnitine induced regression of LVH in patients on hemodialysis, even for those with normal systolic function.

2) CoQ

https://www.ncbi.nlm.nih.gov/pubmed/9266516

All patients noted improvement in symptoms of fatigue and dyspnea with no side effects noted. The mean interventricular septal thickness improved significantly

3) Taurine

https://www.researchgate.net/public...hypertrophy_in_renovascular_hypertensive_rats

Taurine which effectively suppress myocardial cell hypertrophy and collagenous fiber productive reaction by decreasing myocardial local RAAS and c-fos mRNA expression can produce good preventive effect on left ventricle hypertrophy caused by renal hypertension.

4) Testosterone

https://www.ncbi.nlm.nih.gov/pubmed/14713281

The results of the present study are consistent with the hypothesis that lower levels of testosterone in men are associated with higher blood pressure, left ventricular mass, and left ventricular hypertrophy.

5) Vitamin D

https://www.ncbi.nlm.nih.gov/pubmed/15882312

Recent studies using vitamin D receptor deficient mice as a model demonstrate a crucial role of vitamin D in regulation of the renin-angiotensin system. Additionally, there is emerging evidence linking treatment with vitamin D to improved survival on hemodialysis and improvement in cardiac function. The emergence of this data is focusing attention on the previously underappreciated nonmineral homeostatic effects of vitamin D that very likely play an important role in the pathogenesis of cardiac disease in ESRD.

https://www.ncbi.nlm.nih.gov/pubmed/21937207

In the absence of major cardiovascular risk factors, 25(OH)D deficiency is a frequent finding in EH patients and is independently associated with LVH.


Honorable mention) Possibly fish oil:

https://www.ncbi.nlm.nih.gov/pubmed/18360184

In summary, any patient with documented coronary heart disease and those with risk factors for sudden cardiac death, such as left ventricular dysfunction, left ventricular hypertrophy, prior myocardial infarction, or high-grade ventricular dysrhythmias, should consider fish oil supplementation.

Great thread man! And not only do these help LVH, they help every facet of heart chamber growth in general. Keep posting as contributions like this are quite valuable around here.

In regards to septal thickness being helped my CoQ10, this explains why I had an echo cardiogram back in 2012 showing a little bit of that, and then it has never once shown up on an echo cardiogram ever since. The difference is I wasn't on CoQ10/ubiquinol back then but have been ever since.
 

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