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Running tren and hgh together. General thoughts?

mujeriego

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With more and more people noticing a trend on their bloodwork of lower igf1 numbers (or not where they should be at least) when running tren alongside hgh. What are the general thoughts of people around this and any general ideas on why it happens? (liver enzymes? false readings like what tren does with e2? or something else?)

Also are people running the two together still noticing all the positive hgh effects despite the lower igf scores? or do you feel that running hgh along with tren might be a waste?

I've run tren plenty of times and hgh as well, but never actually together so this coming cycle in a month or two will be my first time running them alongside each other. So I'm really curious about this subject
 
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nothuman

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Most effective combo of drugs imagineable
 

ChestRockwell

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With more and more people noticing a trend on their bloodwork of lower igf1 numbers (or not where they should be at least) when running tren alongside hgh.

I would urge folks to challenge the popular mindset that "higher endocrine IGF-1 equals good" as it relates to hypertrophy.

It is far more complicated than this, and a compelling argument could be made that chronically elevated endocrine IGF-1 is impeding the hypertrophy process.
 

KillerStack

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I would urge folks to challenge the popular mindset that "higher endocrine IGF-1 equals good" as it relates to hypertrophy.

It is far more complicated than this, and a compelling argument could be made that chronically elevated endocrine IGF-1 is impeding the hypertrophy process.

Hey, I came across your article on gh for mass on meso yesterday while looking for something else. Some good info :)

Have you thought about how your research could relate to IV gh administration? Could there theoretically be an advantage to doing it IV? I doubt I would ever personally do it; just thinking about it theoretically :D
 

Elvia1023

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it will most likely build muscle and burn some fat

Most effective combo of drugs imagineable

I would urge folks to challenge the popular mindset that "higher endocrine IGF-1 equals good" as it relates to hypertrophy.

It is far more complicated than this, and a compelling argument could be made that chronically elevated endocrine IGF-1 is impeding the hypertrophy process.

:yeahthat:

Nothing more to state really. Tren and hgh and you should be in the position to look your best ever if everything else is in place.
 

ChestRockwell

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Hey, I came across your article on gh for mass on meso yesterday while looking for something else. Some good info :)

Have you thought about how your research could relate to IV gh administration? Could there theoretically be an advantage to doing it IV? I doubt I would ever personally do it; just thinking about it theoretically :D

Right on, I'm glad you liked it!

As far as IV administration goes, there are a lot of reasons it may be superior to either SC or IM injections simply due to some of the pharmacokinetic behaviors I talk about in both the "fat loss" and "hypertrophy" articles. Quite frankly, it best mimics the in vivo secretory profile of GH.

Of course, I refrain from recommending it, simply due to safety concerns.
 

heavyhitter

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Well practically every competitive bodybuilder does it sooooo....
 

mujeriego

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I would urge folks to challenge the popular mindset that "higher endocrine IGF-1 equals good" as it relates to hypertrophy.

It is far more complicated than this, and a compelling argument could be made that chronically elevated endocrine IGF-1 is impeding the hypertrophy process.
I've read your articles on meso too, both the fat burning and hypertrophy protocols. Very well written and informative. They are excellent.

So an educated guess at this point is that igf1 levels are not the be all end all when using hgh as many folk would have you believe
 

ChestRockwell

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I've read your articles on meso too, both the fat burning and hypertrophy protocols. Very well written and informative. They are excellent.

So an educated guess at this point is that igf1 levels are not the be all end all when using hgh as many folk would have you believe

Right on, thanks man - I'm glad you liked them!

And yes, there are a lot of potential reasons why chronically elevated IGF-1 levels may be working against us as it relates to maximal hypertrophy potential. The GH/IGF axis is very complex and has many built in feedback regulators.

There is quite a bit of evidence to suggest that chronically elevated endocrine IGF-1 acts as a negative feedback regulator on autocrine IGF-1, which is very much what we're after in skeletal muscle tissue. So I'm currently of the belief that maximizing autocrine IGF-1 while simultaneously trying to limit how elevated our endocrine IGF-1 levels are would be ideal.
 

ALLEX

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I didn't think tren was all that when I tried it. But I haven't combined it with HGH yet.

Primo seemed like a superior drug for overall look, but I did use pharma back when it was Schering's. Been a while...

I do understand that my experience with tren doesn't say much, as it was a small dose just to try it out. I remember feeling weird and slightly unhealthy and if I don't feel healthy and rested, I have a hard time to grow.

Primo, OTOH, felt like a million bucks. Even skin was better.
 

GreenTLB6

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Love this combo. Especially while dieting.

In an off Season phase the only issue I have run into is getting enough food in to grow more. You’ll need more food with tren alone. Add gh to the mix and it takes my not so great metabolic rate to an all new level. If I can get enough food in I get bigger, stronger, and leaner.
 

rmtt

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Love this combo. Especially while dieting.

In an off Season phase the only issue I have run into is getting enough food in to grow more. You’ll need more food with tren alone. Add gh to the mix and it takes my not so great metabolic rate to an all new level. If I can get enough food in I get bigger, stronger, and leaner.
Same here. Tren by itself makes it hard enough to eat enough food to gain. I still have an appetite, but would start dropping weight at my small calorie surplus. With gh in the mix, I would have to be stuffing my face all day to gain any weight.



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GreenTLB6

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Same here. Tren by itself makes it hard enough to eat enough food to gain. I still have an appetite, but would start dropping weight at my small calorie surplus. With gh in the mix, I would have to be stuffing my face all day to gain any weight.



Sent from my LG-H871 using Tapatalk

Yup. This is me. It’s gets to be not fun.
 

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