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Study Shows Amino Acids Can Prevent Brain Injuries

marssel

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Considering it all I’m not really in pain. The knee is a damn unit! I want to get the other one replaced and nothing is wrong with it. I don’t even take pain meds
So your robo knee is better than your real one? Is it fucking VA issue?
 

fisther69

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So your robo knee is better than your real one? Is it fucking VA issue?
My robo knee is 100% an unfair advantage.

I ditched the VA and I’m on my wife’s insurance..she’s a cardio thoracic surgeon..I’m well taken care of lol
 

emeric delczeg

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emeric delczeg

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An endogenous cannabinoid (2-AG) is neuroprotective after brain injury​

D Panikashvili 1, C Simeonidou, S Ben-Shabat, L Hanus, A Breuer, R Mechoulam, E Shohami
Affiliations expand

Abstract​

Traumatic brain injury triggers the accumulation of harmful mediators that may lead to secondary damage. Protective mechanisms to attenuate damage are also set in motion. 2-Arachidonoyl glycerol (2-AG) is an endogenous cannabinoid, identified both in the periphery and in the brain, but its physiological roles have been only partially clarified. Here we show that, after injury to the mouse brain, 2-AG may have a neuroprotective role in which the cannabinoid system is involved. After closed head injury (CHI) in mice, the level of endogenous 2-AG was significantly elevated. We administered synthetic 2-AG to mice after CHI and found significant reduction of brain oedema, better clinical recovery, reduced infarct volume and reduced hippocampal cell death compared with controls. When 2-AG was administered together with additional inactive 2-acyl-glycerols that are normally present in the brain, functional recovery was significantly enhanced. The beneficial effect of 2-AG was dose-dependently attenuated by SR-141761A, an antagonist of the CB1 cannabinoid receptor.

Components of the eCB system, including ligands 2-AG and AEA, CB1 receptor and metabolizing enzymes DAGL, NAPE-PLD, MAGL and FAAH, are present in the very early chick embryos, and suggest that the functionally active CB1 receptor mediated signaling might play a critical role in the early stages of neurogenesis.
 

emeric delczeg

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An endogenous cannabinoid (2-AG) is neuroprotective after brain injury​

D Panikashvili 1, C Simeonidou, S Ben-Shabat, L Hanus, A Breuer, R Mechoulam, E Shohami
Affiliations expand

Abstract​

Traumatic brain injury triggers the accumulation of harmful mediators that may lead to secondary damage. Protective mechanisms to attenuate damage are also set in motion. 2-Arachidonoyl glycerol (2-AG) is an endogenous cannabinoid, identified both in the periphery and in the brain, but its physiological roles have been only partially clarified. Here we show that, after injury to the mouse brain, 2-AG may have a neuroprotective role in which the cannabinoid system is involved. After closed head injury (CHI) in mice, the level of endogenous 2-AG was significantly elevated. We administered synthetic 2-AG to mice after CHI and found significant reduction of brain oedema, better clinical recovery, reduced infarct volume and reduced hippocampal cell death compared with controls. When 2-AG was administered together with additional inactive 2-acyl-glycerols that are normally present in the brain, functional recovery was significantly enhanced. The beneficial effect of 2-AG was dose-dependently attenuated by SR-141761A, an antagonist of the CB1 cannabinoid receptor.

Components of the eCB system, including ligands 2-AG and AEA, CB1 receptor and metabolizing enzymes DAGL, NAPE-PLD, MAGL and FAAH, are present in the very early chick embryos.
 

marssel

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My robo knee is 100% an unfair advantage.

I ditched the VA and I’m on my wife’s insurance..she’s a cardio thoracic surgeon..I’m well taken care of lol
Fucking a mine is a shrink and I thought I was getting over easy, lol, congrats
 

fisther69

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Jan 15, 2022
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Fucking a mine is a shrink and I thought I was getting over easy, lol, congrats
Yeah, I almost picked up my insurance at my new job before my wife stopped my ass..glad she did lol
 

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