The main thing is diet and getting the fat off. Combining that with synthergine would only help improve overall liver health. Synthergine contains many useful ingredients that help restore the liver in a variety of ways. DADA is one of it's ingredients and has been shown to help with fatty liver disease. Here is a quote from an article I wrote on synthergine years ago...
"Di-isopropylamine Dichloroacetate (DADA) aids in the detoxification of metallic and chemical metabolites. It also increases cortical glucose uptake and oxygen utilization. There is increasing documentation on DADA's incredible liver conditioning abilities. Lu LG et al. (2005) looked into DADA's effects on nonalcoholic fatty liver diseases. Over a treatment period of 8 weeks, both high and low dosage groups showed dramatic improvements in clinical symptoms, serum lipids and liver alteration severity. Most patients had their ALT numbers normalize by the end of the 8 week treatment. Moreover in all dosage groups no severe drug reactions were found and only 2 cases (1.6%) experienced any negative reaction and that was dryness of the mouth."
Here is an abstract from the actual study...
Abstract
To investigate the efficacy and safety of diisopropylamine dichloroacetate in the treatment of nonalcoholic fatty liver diseases (NAFLD). A randomized, double-blind, dose-paralleled control trial was carried out with NAFLD patients. The patients were randomly assigned to 2 groups treated with either a high dosage (120 mg/d) or a low dosage (60 mg/d) of diisopropylamine dichloroacetate for 8 weeks and the efficacy and safety of the drug were examined. 127 cases were recruited for the trial, 63 in the high dosage group, and 64 in the low dosage group. No case dropped out in the trial but four cases were eliminated (4/127, 3.1%). The final number in this trial was 123, with 61 in the high dosage group and 62 in the low dosage group. After 8 weeks of treatment, the overall improvement of clinical symptoms in the high dosage and in the low dosage group was 87.8% and 79.6%, respectively. ALT normalization was found in 55.7% and 69.4% of the cases in the two groups, serum lipids were lowered in 67.2% and 67.7% and ultrasound grading of the liver alteration severity was lowered in 51.7% and 43.5% in the two groups. The differences found between the two groups were of no statistical significance. One case from each group was found having an adverse drug reaction of dryness of the mouth (1.6%). No severe adverse drug reactions were found. Diisopropylamine dichloroacetate could be used as a safe and effective drug in the treatment of nonalcoholic fatty liver diseases.