TRUE OR FALSE: Benedryl cleans your receptors

[TheChisle]

Just wondering if this is true, if you know anything on this, please discuss, thanks

 

[Rockefeller]

Cleans receptors for clen or anabolics?

 

[TheChisle]

anything...

 

[Fa Seeshus]

clears my "hay fever" receptors rather well.



you need to be more specific about this.

 

[td1111]

Personally, I found it useless for making clen effective again. Ironically, it also does nothing for my allergies, but puts me to sleep easily.

 

[GoneForever]

I thought saturated receptors from gear was a myth?

 

[gordo14]

Try the search function........

"Benadryl is sold as an anti-histimine in the United States, and/or a sleep aid elsewhere in the world. However, Beta receptors are embedded in the cell's outer phospholipid membrane. The stability of the membrane has a lot to do with the proper function of the receptors. Methylation of the phospholipids is stimulated by the binding of beta agonists to their receptors. Methylated phospholipids are foreign to the body, and when the body recognizes them as foreign, it breaks them down with phospholipase A2. This changes the structure of the outer membrane which results in desensitizaton of the beta receptors. On the other hand, agents that inhibit phospholipase A2 slow desensitization.

Cationic ampiphylic drugs are known for their ability to inhibit phospholipase A2. Benadryl (diphenhydramine) is a cationic ampiphylic drug.

Ergo, Benadryl slows desensitization of Beta receptors (i.e. Upgrades them) by inhibiting phospholipase A2, which is the enzyme that breaks down methylated phospholipids, and this action in turn keeps the phospholipid membrane stable, and thus keeps the receptors functioning properly.

Reference:

Prog Clin Biol Res. 1981;63:383-8.
Phospholipid methylation: a possible mechanism of signal transduction across biomembranes.
Hirata F, Tallman JF, Henneberry RC, Mallorga P, Strittmatter WJ, Axelrod J"

So yes benedryl can help the receptors. It is as with everything else though.....everyone is different and there bodies don't always respond the same. Most use Clen and every 3rd week throw in 7 days of the benedryl. Also some people use ketofin(spelling might be wrong) works pretty much the same way as the benedryl. And others use the clen for 2 weeks then an eca stack for 2 weeks. This is gonna sound bad, but its your body.....you may have to experiment to see what works.