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Extremely low Pregnenolone!

Thebigone

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Oct 28, 2009
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I’ve gotten pretty much every hormone test you could think of but completely forgot about Pregnenolone. I’m on TRT/hcg and my doctor usually tests all my hormones including progesterone but somehow negated pregnenolone. So I ordered the test and just got my results back and wow!

Pregnenolone LC/MS <5 range 22-237

Now I have to look up all the symptoms of low Pregnenolone. I’ve got a bottle of Douglas Labs Pregnenolone I’ll start ASAP. What’s the recommended dosage? Anyone ever have low levels and supplement with it? If so what were the benefits?

Thanks
 

Thebigone

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Update:
I was looking through some old lab work and I noticed in May 2017 I had pregnenolone testedand it was normal
26 range 13-208 nd/dL

Back in 2015 my progesterone was about 4x the range but I was on Deca back then which increase it.

So this is all of that within only one year my pregnenolone went from 26 to <5. My TRT regimen has been the exact same so I’m puzzled.

Going to get a progesterone test done this week as well.
 

superbigd

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Bumping this cuz I’m curious to hear more from the experts. Do you take HCG? Test with anti estrogen without HCG will shut you down
 

Thebigone

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Bumping this cuz I’m curious to hear more from the experts. Do you take HCG? Test with anti estrogen without HCG will shut you down


Yes I take hcg at 250iu 3x/wk along with my TRT. Normally I use low dose arimidex but this last Time around I dropped it and my estrogen was high
43 range <29

I wonder if the high estrogen caused the significant drop in pregnenolone?
 

totalrecomp

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Iconic Formulations makes a topical preg if the oral does not bring your levels up.
 

jcc80

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Well... I never had pregnenolone tested, but I had read about its production being suppressedp by AAS and TRT. Decided to start supplementing 50mg per day and just noticed a sense of overall more well being. After running out, I gradually started feeling a little more down.

So I just kept it going. I'm using 100mg caps now, but I'm guessing that might be too much.

Sent from my SM-G950U using Tapatalk
 

lntense

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Curious others experiences supplementing with pregenolone.
 

KillerStack

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There was this company selling topical pregnenolone
a long time ago which claimed prgnenolone helped trenbolone induced bad mood, anxiety etc. Never tried it but maybe someone here has.
 

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