I'm on doc prescribed TRT at 175 mg of test cyp weekly and my estradiol is 112. WTF?

[Jake LaMotta]

I'm on doc prescribed TRT (at 29 years old) at 175 mg injections of test cyp weekly. I just got some bloodwork back (I get my shots every Thurs afternoon, this draw was taken Thursday morning BEFORE my shot) and my test came out to be 949 ng/dL and my estradiol is 112 pg/mL (should be <=54 pg/mL). I'm also taking DHEA 50 mg daily (25 mg morning/25 mg evening) and NatureThroid 1/12 grain daily.

Over the last 9 months my doc (a wellness doctor) has slowly been upping my test dosage (from weekly injections of 125 mg to 150 mg to 175 mg). And as my test ng/dL has been rising so has my estradiol pg/mL. He had me taking Indole Forte for a couple months. That didn't work and my estradiol raised. Than he had me taking Calcium D-Glucorate for a couple of months. That didn't work and my estradiol raised.

Now this is my problem:

Over the last 6 weeks I noticed something: my erections ARE WEAK AS HELL. I'm talking very small. I can't understand it because my sex drive is through the roof. And plus my testosterone is very high so I'm baffled. My doc says even though my test is high, my estrogen is also very high and that is what is keeping my erections from being real hard and stiff. He said my estradiol should be 40 pg/mL. I also asked if the DHEA (which I know can convert to test and ESPECIALLY estrogen in men) could be causing this. He said no way would DHEA be causing your estrogen to sky rocket like this.

My solution was to add Arimidex to the mix (which I've been suggesting to him for months). His response: I do not prescribe that because of all the side effects. I will never prescribe you any anti estrogen other than Indole Forte, Calcium D-Glucorate, or Progesterone cream. So I asked what do we do next? He said he will lower my test from 175 mg weekly to 125 mg weekly. I asked if that didn't work what do we do. He said we could than try a Progesterone cream.

He also mentioned maybe my ED problems are something more and I should maybe see a Urologist for some tests. I don't think that's the case because a couple months ago I was getting rock solid.

I'm confused more than ever.

A few questions:

1. Even though my test is high, would my high estrogen be causing ED?

2. Even though I'm taking no anti estrogens right now, would him lowering my test dosage from 175 mg to 125 mg weekly lower my estrogen to normal levels? How long will it take? Should I even have him go lower and only give me 100 mg of test a week?

3. If all else fails, and I start taking the progesterone creme...would that work? Is Progesterone an effective anti estrogen? How long will it take to work?

4. How do you explain that my sex drive is through the roof but I can't get it up?

5. I have a meeting with an endocrinologist Tuesday. I'm going to get a second opinion. Do endocrinologists presrcibe arimidex to men with my situation or am I wasting my time?

A couple points:

*Last year before I got on TRT my test was real low (206 ng/dL) and because of that I had ED. Since I got on TRT (until a couple months ago) I had NO ED PROBLEMS WHAT SO EVER.

*For those of you who will suggest I go see another doctor, there is no other TRT doctor anywhere near where I live. He is the only one. And he vehemently will not prescribe Arimidex. I'm stuck with him.

*I refuse to go black market to get AI's. That's not even an option.

*My doc is not a primary doc, endocrinologist, or urologist. He is a progressive medicine/wellness doc who specializes in TRT.

Someone please help me make sense of this.

 

[VNV]

Easy. Your estradiol is about twice as high as it should be because your test levels are about twice as high as they should be. Take an AI or decrease your weekly test. dosage.

 

[MrCyp]

You must be estrogen prone b/c your test is just slightly higher than the range but your estro is double. Test should be at 220-850 and estro <52 I think his advice is decent. Try 125 and see what happens. It may drop your T levels down to the 600 or 700 range but thats still very good. Thats abou what a 25yr old male should be. Your estro should significantly drop from that as well. And dhea could play a small part but a very small part at only 50mg/day. But one ? why progesterone cream? Thats adding a hormone that men shouldnt have.

 

[Jake LaMotta]

...Try 125 and see what happens. It may drop your T levels down to the 600 or 700 range but thats still very good. Thats about what a 25yr old male should be. Your estro should significantly drop from that as well...

What if I have him drop it to 100 mg weekly? Will that get my estrogen to normal levels? Will that lower my testosterone too much?

 

[Quad-smack]

Look into AIFM or some exemestane from one of the sponsors. High Estradiol in men is not good...

 

[Ehren]

Good catch, Quad-smack. AIFM is a good stuff and legal. That's a solid solution right there. And I love Aromasin (Exemestane), not much bad your doc could say about it. Adex, he can point to the effect on lipid profile., and E2 rebound, but not with Aromasin.

Nolvadex would do about nil to sort you out. Block estro action in the breast tissue, but do nothing about circulating E2 (doing nothing for ED). Its not an AI and in this case he's right, bad for ya liver and not a good long term solution. Shit KILLS my sex drive.

As an aside, why would you not consider AI's from outside sources? Is it a question of safety or legality? I respect it, Im just wondering. When it comes to my unit functioning, all bets are off. I'd get whatever I needed to, from wherever.

 

[buck]

1. Yes it could. The body tries to keep things in balance and your numbers are way out there.
2. It should lower your E2 levels but you would still need to be tested to see if you were in the normal range. Some men have had good luck splitting there weekly dosage so there is not such a high spike in E2 levels.
3. I have never heard of the creme clearing out that much E2.
4. Sex drive is in the brain. ED can be caused by problems down below.

You could look into DIM as it is natural and has helped some men with E2 problems. My Dr. has suggested it before.
If you self inject try splitting your dosage and see what that does.

 

[Kaladryn]

All the side effects from Arimidex are from lowering E2 too much, it doesn't have any direct side effects other than that from what I understand.

 

[Jake LaMotta]

I have a meeting with an endocrinologist Tuesday. I'm going to get a second opinion. Do endocrinologists presrcibe arimidex to men with my situation or am I wasting my time?

 

[Quad-smack]

A little light reading for you. I like this study because of the direct application to males...
Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males -- Mauras et al. 88 (12): 5951 -- Journal of Clinical Endocrinology & Metabolism

 

[Jake LaMotta]

A little light reading for you. I like this study because of the direct application to males...
Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males -- Mauras et al. 88 (12): 5951 -- Journal of Clinical Endocrinology & Metabolism

He won't prescribe that.

 

[MrCyp]

What if I have him drop it to 100 mg weekly? Will that get my estrogen to normal levels? Will that lower my testosterone too much?

You have to keep playing with levels and finally see what works. I think 120 will work for yah but you just gotta wait and see. takes a good 2months to really see the change in the bloodwork

 

[Jake LaMotta]

You have to keep playing with levels and finally see what works. I think 120 will work for yah but you just gotta wait and see. takes a good 2months to really see the change in the bloodwork

You think dropping my test dosage to 120 mg a week will get my estradiol levels normal?

 

[ericraven2003]

You think dropping my test dosage to 120 mg a week will get my estradiol levels normal?

Why wouldn't you get a bit of arimidex from a board sponsor? Its oral and all the same chemical. It will be no different then getting a script. Hell, there are online pharmacies that sell it as well.Having high estrogen is not great and dropping your test dosage will take a while to have any effect.

 

[Jake LaMotta]

What board sponsor? Is it the real thing? How is that legal without a script?

 

[ericraven2003]

What board sponsor? Is it the real thing? How is that legal without a script?

Researchstop has anti E's. It is sold as research chemicals so no prescription needed.

Yes its real. Its the only way I get mine. GAUL's has very cheap arimidex too.

 

[MrCyp]

You think dropping my test dosage to 120 mg a week will get my estradiol levels normal?

It will def lower them from what they are now but only a bloodtest will show if it lowered them enough.

 

[emeric delczeg]

I'm on doc prescribed TRT (at 29 years old) at 175 mg injections of test cyp weekly. I just got some bloodwork back and my test came out to be 949 ng/dL and my estradiol is 112 pg/mL (should be <=54 pg/mL). WTF? I'm also taking DHEA 50 mg daily (25 mg morning/25 mg evening) and NatureThroid 1/12 grain daily.

Over the last 9 months my doc (a wellness doctor) has slowly been upping my test dosage (from weekly injections of 125 mg to 150 mg to 175 mg). And as my test ng/dL has been rising so has my estradiol pg/mL. He had me taking Indole Forte for a couple months. That didn't work and my estradiol raised. Than he had me taking Calcium D-Glucorate for a couple of months. That didn't work and my estradiol raised.

Now this is my problem:

Over the last 6 weeks I noticed something: my erections ARE WEAK AS HELL. I'm talking very small. I can't understand it because my sex drive is through the roof. And plus my testosterone is very high so I'm baffled. My doc says even though my test is high, my estrogen is also very high and that is what is keeping my erections from being real hard and stiff. He said my estradiol should be 40 pg/mL. I also asked if the DHEA (which I know can convert to test and ESPECIALLY estrogen in men) could be causing this. He said no way would DHEA be causing your estrogen to sky rocket like this.

My solution was to add Arimidex or Nolvadex to the mix (which I've been suggesting to him for months). His response: I do not prescribe those because of all the side effects. I will never prescribe you those. So I asked what do we do next? He said he will lower my test from 175 mg weekly to 125 mg weekly. I asked if that didn't work what do we do. He said we could than try a progesterone creme.

He also mentioned maybe my ED problems are something more and I should maybe see a Urologist for some tests. I don't think that's the case because a couple months ago I was getting rock solid.

I'm confused more than ever.

A few questions:

1. Even though my test is high, would my high estrogen be causing ED?

2. Even though I'm taking no anti estrogens right now, would him lowering my test dosage from 175 mg to 125 mg weekly lower my estrogen to normal levels? How long will it take? Should I even have him go lower and only give me 100 mg of test a week?

3. If all else fails, and I start taking the progesterone creme...would that work? Is progesterone creme an effective anti estrogen? How long will it take to work?

4. How do you explain that my sex drive is through the roof but I can't get it up?

A couple points:

*Last year before I got on TRT my test was real low (206 ng/dL) and because of that I had ED. Since I got on TRT (until a couple months ago) I had NO ED PROBLEMS WHAT SO EVER.

*For those of you who will suggest I go see another doctor, there is no other TRT doctor anywhere near where I live. He is the only one. And he vehemently will not prescribe Arimidex or Nolvadex. I'm stuck with him.

*I refuse to go black market to get AI's. That's not even an option.

Someone please help me make sense of this.

You MD is wrong regarding the DHEA, stop the DHEA and start taking Humanofort with the test, you will be very happy with the result.

 

[emeric delczeg]

You think dropping my test dosage to 120 mg a week will get my estradiol levels normal?

Drop the DHEA and the problem will be solved.

 

[Jake LaMotta]

Drop the DHEA and the problem will be solved.

Here's the problem: When I don't take DHEA my DHEA levels are low. Should I just get off it and live with the low DHEA levels? Could you live a quality life with good sexual function with low DHEA levels?